Diabetes Does not Affect Outcome of Symptomatic Carotid Stenosis Treated with Endovascular TechniquesLago A. · Parkhutik V. · Tembl J.I. · Bermejo A. · Aparici F. · Mainar E. · Vázquez-Añón V.
Departments of aNeurology, bRadiology, Hospital Universitari la Fe, Valencia, Spain
Background: The influence of diabetes on carotid revascularization techniques is controversial, with few data regarding angioplasty and stenting (CAS). Our purpose was to analyze whether its presence constitutes a risk factor for poor outcome of patients with carotid stenosis treated with CAS. Methods: We compared 30-day and long term morbidity and mortality, as well as restenosis rates, of non diabetic and diabetic patients with symptomatic carotid stenosis treated with endovascular techniques. Results: 318 consecutive patients, 116 (36.5%) of them diabetics, were followed for a median of 56 months. Cumulative 30-day stroke, ischemic cardiopathy and death rate was 4% for non diabetics and 5.2% for diabetics (non significant). Long term stroke and mortality rate was 26.4% for the first group and 34.3% for the second (non significant). The most frequent causes of death were myocardial infarction (17.5% non diabetics, 44% diabetics, p = 0.04), ischemic stroke (12.5% non diabetics, 4% diabetics, non significant) and cancer (30% non diabetics, 16% diabetics, non significant). Twelve patients (6.4%) had restenosis ≥50%, 5.9% non diabetic, 7.4% diabetic, also without statistical significance. Conclusions: In our series, endovascular treatment is both efficient and safe in diabetic patients with symptomatic carotid stenosis; therefore, the presence of diabetes mellitus did not increase the risks linked to CAS procedure.
Aida Lago, MD, PhD
Hospital Universitari la Fe, Neurology Department
Avenida Bulevard Perifèric Sud, S/N
ES-46026 Valencia (Spain)
Received: March 13, 2012
Accepted: November 19, 2012
Published online: February 20, 2013
Number of Print Pages : 7
Number of Figures : 1, Number of Tables : 3, Number of References : 33
Vol. 69, No. 5, Year 2013 (Cover Date: May 2013)
Journal Editor: Bogousslavsky J. (Montreux)
ISSN: 0014-3022 (Print), eISSN: 1421-9913 (Online)
For additional information: http://www.karger.com/ENE