Cover

Brain, Stroke and Kidney

Editor(s): Toyoda K. (Osaka) 
Table of Contents
Vol. 179, 2013
Section title: Underlying Concepts for Cerebrorenal Interaction
Toyoda K (ed): Brain, Stroke and Kidney. Contrib Nephrol. Basel, Karger, 2013, vol 179, pp 15-23
(DOI:10.1159/000346718)

Obesity and Heart Failure as a Mediator of the Cerebrorenal Interaction

Jindal A. · Whaley-Connell A. · Sowers J.R.
Department of Internal Medicine, University of Missouri, Columbia, Mo., USA

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Article / Publication Details

Published online: 5/3/2013
Cover Date: 2013

Number of Print Pages: 9
Number of Figures: 1
Number of Tables: 0

ISBN: 978-3-318-02351-0 (Print)
eISBN: 978-3-318-02352-7 (Online)

Abstract

The obesity epidemic is contributing substantially to the burden of cardiovascular disease including heart disease and congestive heart failure, in the United States and the rest of the world. Overnutrition as a driver of obesity, promotes alterations in fatty acid, lipid, and glucose metabolism that influence myocardial function and progression of heart failure from diastolic to systolic failure. The association of progressive heart failure and progressive chronic kidney disease is well documented and often referred to as the cardiorenal syndrome, as well as a prognosticator for cerebrovascular disease (e.g. stroke). Whether the relationship between obesity, heart disease/failure and risk for chronic kidney disease and stroke is direct or a confluence of risk factors is poorly understood.


  

Author Contacts

James R. Sowers, MD
Diabetes and Cardiovascular Center of Excellence
Columbia School of Medicine, University of Missouri
One Hospital Drive, Columbia, MO 65212 (USA)
E-Mail sowersj@health.missouri.edu

  

Article Information

Published online: May 03, 2013
Number of Print Pages : 9
Number of Figures : 1, Number of Tables : 0, Number of References : 38

  

Publication Details

Book Serie: Contributions to Nephrology, Vol. 179, Year 2013

Editor(s): Toyoda, K. (Osaka)
ISSN: 0302-5144 (Print), eISSN: 1662-2782 (Online)

For additional information:
http://www.karger.com?issn=0302-5144

Book Title: Brain, Stroke and Kidney

Editor(s): Toyoda K (ed)

For additional information:
http://www.karger.com?issn=0302-5144&volume=179


Article / Publication Details

Published online: 5/3/2013
Cover Date: 2013

Number of Print Pages: 9
Number of Figures: 1
Number of Tables: 0

ISBN: 978-3-318-02351-0 (Print)
eISBN: 978-3-318-02352-7 (Online)


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Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in goverment regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
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