The obesity epidemic is contributing substantially to the burden of cardiovascular disease including heart disease and congestive heart failure, in the United States and the rest of the world. Overnutrition as a driver of obesity, promotes alterations in fatty acid, lipid, and glucose metabolism that influence myocardial function and progression of heart failure from diastolic to systolic failure. The association of progressive heart failure and progressive chronic kidney disease is well documented and often referred to as the cardiorenal syndrome, as well as a prognosticator for cerebrovascular disease (e.g. stroke). Whether the relationship between obesity, heart disease/failure and risk for chronic kidney disease and stroke is direct or a confluence of risk factors is poorly understood.
© 2013 S. Karger AG, Basel
James R. Sowers, MD
Diabetes and Cardiovascular Center of Excellence
Columbia School of Medicine, University of Missouri
One Hospital Drive, Columbia, MO 65212 (USA)
Published online: May 03, 2013
Number of Print Pages : 9
Number of Figures : 1, Number of Tables : 0, Number of References : 38
Book Serie: Contributions to Nephrology, Vol. 179, Year 2013
Editor(s): Toyoda, K. (Osaka)
ISSN: 0302-5144 (Print), eISSN: 1662-2782 (Online)
For additional information:
Book Title: Brain, Stroke and Kidney
Editor(s): Toyoda K (ed)
For additional information:
Article / Publication Details
Published online: 5/3/2013
Cover Date: 2013
Number of Print Pages: 9
Number of Figures: 1
Number of Tables: 0
ISBN: 978-3-318-02351-0 (Print)
eISBN: 978-3-318-02352-7 (Online)
Copyright / Drug Dosage
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