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Vol. 161, No. 3, 2013
Issue release date: June 2013
Section title: Review
Int Arch Allergy Immunol 2013;161:197-204
(DOI:10.1159/000346896)

Parameters Associated with Chronic Spontaneous Urticaria Duration and Severity: A Systematic Review

Rabelo-Filardi R. · Daltro-Oliveira R. · Campos R.A.
aUniversidade Federal da Bahia, and bServiço de Imunologia, Hospital das Clínicas Professor Edgard Santos, Salvador, Brazil

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Article / Publication Details

First-Page Preview
Abstract of Review

Published online: 3/15/2013

Number of Print Pages: 8
Number of Figures: 0
Number of Tables: 2

ISSN: 1018-2438 (Print)
eISSN: 1423-0097 (Online)

For additional information: http://www.karger.com/IAA

Abstract

Background: Although some authors have already evaluated the predictive value of various parameters regarding the duration of chronic spontaneous urticaria (CSU), it remains uncertain which ones have importance in clinical practice as prognostic factors that indeed enable prediction. Similarly, some authors have investigated parameters that might be related to severe cases of CSU. However, the results of studies evaluating several parameters as markers of disease severity are fragmented. Thus, we performed a systematic review to summarize the findings of studies investigating the parameters associated with CSU duration and severity. Methods: Two authors independently searched PubMed until June 2012 for observational retrospective or prospective studies addressing clinical or laboratory parameters associated with disease duration or severity in CSU patients. Results: We found 1,136 potentially relevant published papers related to the subject, 34 of which were included in the systematic review. A total of 16, 6 and 12 articles evaluated CSU parameters on severity, duration or both, respectively. Conclusions: Our findings suggest that disease severity might predict CSU duration. Similarly, evidence suggests that plasma levels of prothrombin fragment 1 + 2, D-dimer and C-reactive protein may function as markers of CSU severity.


  

Author Contacts

Correspondence to: Dr. Régis A. Campos
Serviço de Imunologia, Hospital das Clínicas Professor Edgard Santos
Rua João das Botas, s/n, Canela, 5° andar
Salvador, Bahia, CEP 40.110-060 (Brazil)
E-Mail regisacampos@gmail.com

  

Article Information

Published online: March 15, 2013
Number of Print Pages : 8
Number of Figures : 0, Number of Tables : 2, Number of References : 44

  

Publication Details

International Archives of Allergy and Immunology

Vol. 161, No. 3, Year 2013 (Cover Date: June 2013)

Journal Editor: Valenta R. (Vienna), Bohle B. (Vienna)
ISSN: 1018-2438 (Print), eISSN: 1423-0097 (Online)

For additional information: http://www.karger.com/IAA


Article / Publication Details

First-Page Preview
Abstract of Review

Published online: 3/15/2013

Number of Print Pages: 8
Number of Figures: 0
Number of Tables: 2

ISSN: 1018-2438 (Print)
eISSN: 1423-0097 (Online)

For additional information: http://www.karger.com/IAA


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