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Vol. 47, No. 4, 2014
Issue release date: June 2014
Section title: Original Paper
Psychopathology 2014;47:261-269
(DOI:10.1159/000357813)

Capgras' Syndrome in First-Episode Psychotic Disorders

Salvatore P. · Bhuvaneswar C. · Tohen M. · Khalsa H.-M.K. · Maggini C. · Baldessarini R.J.
aDepartment of Psychiatry, Harvard Medical School, Boston, Mass., bInternational Consortium for Bipolar and Psychotic Disorders Research, McLean Hospital, Belmont, Mass., cDepartment of Psychiatry, University of Massachusetts, Worcester, Mass., and dDepartment of Psychiatry, University of New Mexico Health Science Center, Albuquerque, N.Mex., USA; eSection of Psychiatry, Department of Neuroscience, University of Parma, Parma, Italy

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Article / Publication Details

First-Page Preview
Abstract of Original Paper

Received: 1/23/2013 8:07:40 AM
Accepted: 12/8/2013
Published online: 2/7/2014

Number of Print Pages: 9
Number of Figures: 0
Number of Tables: 2

ISSN: 0254-4962 (Print)
eISSN: 1423-033X (Online)

For additional information: http://www.karger.com/PSP

Abstract

Background: Misidentification phenomena, including the delusion of ‘imposters' named after Joseph Capgras, occur in various major psychiatric and neurological disorders but have rarely been studied systematically in broad samples of modern patients. This study investigated the prevalence and correlated clinical factors of Capgras' phenomenon in a broad sample of patient-subjects with first-lifetime episodes of psychotic affective and nonaffective disorders. Methods: We evaluated 517 initially hospitalized, first-episode psychotic-disorder patients for the prevalence of Capgras' phenomenon and its association with DSM-IV-TR diagnoses including schizophreniform, brief psychotic, unspecified psychotic, delusional, and schizoaffective disorders, schizophrenia, bipolar-I disorder and major depression with psychotic features, and with characteristics of interest including antecedent psychiatric and neurological morbidity, onset type and presenting psychopathological phenomena, using standard bivariate and multivariate statistical methods. Results: Capgras' syndrome was identified in 73/517 (14.1%) patients (8.2-50% across diagnoses). Risk was greatest with acute or brief psychotic disorders (schizophreniform psychoses 50%, brief psychoses 34.8%, or unspecified psychoses 23.9%), intermediate in major depression (15%), schizophrenia (11.4%) and delusional disorder (11.1%), and lowest in bipolar-I (10.3%) and schizoaffective disorders (8.2%). Associated were somatosensory, olfactory and tactile hallucinations, Schneiderian (especially delusional perception), and cycloid features including polymorphous psychotic phenomena, rapidly shifting psychomotor and affective symptoms, pananxiety, ecstasy, overconcern with death, and perplexity or confusion, as well as rapid onset, but not sex, age, abuse history, dissociative features, or indications of neurological disorders. Conclusions: Capgras' syndrome was prevalent across a broad spectrum of first-episode psychotic disorders, most often in acute psychoses of rapid onset.


  

Author Contacts

Dr. Paola Salvatore
McLean Hospital
115 Mill Street
Belmont, MA 02478-9106 (USA)
E-Mail psalvatore@mclean.harvard.edu

  

Article Information

Received: January 23, 2013
Accepted after revision: December 8, 2013
Published online: February 7, 2014
Number of Print Pages : 9
Number of Figures : 0, Number of Tables : 2, Number of References : 70

  

Publication Details

Psychopathology (International Journal of Descriptive and Experimental Psychopathology, Phenomenology and Psychiatric Diagnosis)

Vol. 47, No. 4, Year 2014 (Cover Date: June 2014)

Journal Editor: Herpertz S.C. (Heidelberg), Fuchs T. (Heidelberg)
ISSN: 0254-4962 (Print), eISSN: 1423-033X (Online)

For additional information: http://www.karger.com/PSP


Article / Publication Details

First-Page Preview
Abstract of Original Paper

Received: 1/23/2013 8:07:40 AM
Accepted: 12/8/2013
Published online: 2/7/2014

Number of Print Pages: 9
Number of Figures: 0
Number of Tables: 2

ISSN: 0254-4962 (Print)
eISSN: 1423-033X (Online)

For additional information: http://www.karger.com/PSP


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