Effect of Ozone on Red Blood Cell Enzymes and IntermediatesZimran A. · Wasser G. · Forman L. · Gelbart T. · Beutler E.
aDepartment of Medicine, Shaare-Zedek Medical Center, Jerusalem, Israel; bInstitute of Environmental Medicine, Erfurt, Germany; cDepartment of Molecular and Experimental Medicine, The Scripps Research Institute, La Jolla, Calif., USA
Ozone autohemotherapy has been considered a form of alternative medicine and has not yet been subjected to the rigors of well-designed clinical trials. Despite encouraging anecdotal reports regarding the use of ozone in various disorders, there has been a concern that ozone per se may adversely affect red cell membranes and metabolites. The purpose of this study was to ascertain the effect of ozone administration at a concentration commonly used in autohemotherapy on a panel of red cell enzymes and intermediates, as well as its effect on red cell integrity. Since these parameters were unaffected by ozone, we suggest that clinical trials for the use of ozone autohemotherapy should be encouraged.
Ari Zimran, MD
Gaucher Clinic, Shaare-Zedek Medical Center
PO Box 3235, Jerusalem 91031 (Israel)
Tel. +972 2 655 5330 or +972 2 655 5673, Fax +972 2 651 7979
Received: Received: July 12, 1999
Accepted: July 12, 1999
Number of Print Pages : 4
Number of Figures : 3, Number of Tables : 1, Number of References : 8
Affiliated with Molecular Biology of Hematopoiesis Symposium
Vol. 102, No. 3, Year 1999 (Cover Date: Released January 2000)
Journal Editor: I. Ben-Bassat, Tel Hashomer
ISSN: 0001–5792 (print), 1421–9662 (Online)
For additional information: http://www.karger.com/journals/aha