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Table of Contents
Vol. 81, Suppl. 1, 1999
Issue release date: Released December 1998
Section title: Paper
Nephron 1999;81(suppl 1):31–37
(DOI:10.1159/000046296)

Urine Volume: Stone Risk Factor and Preventive Measure

Borghi L. · Meschi T. · Schianchi T. · Briganti A. · Guerra A. · Allegri F. · Novarini A.
Istituto di Semeiotica Medica, Università di Parma, Italia

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Article / Publication Details

First-Page Preview
Abstract of Paper

Published online: 12/24/1998
Issue release date: Released December 1998

Number of Print Pages: 7
Number of Figures: 1
Number of Tables: 1

ISSN: 1660-8151 (Print)
eISSN: 2235-3186 (Online)

For additional information: http://www.karger.com/NEF

Abstract

Background: A high fluid intake is the oldest existing treatment for kidney stones, and, up until a few decades ago, it was the only preventive measure at the physician’s disposal for stone recurrences. Methods: Using the data available in literature and partly unpublished personal research, we examine the role of urine volume as a stone risk factor, its impact on calcium crystallization mechanisms and its real importance as a means of prevention. Results: To sum up, the most important findings are: (1) a low urine volume must be considered as a real risk factor, both as regards the onset of renal calculi and stone relapses; (2) an increase in urine volume induced by a high water intake produces favourable effects on the crystallization of calcium oxalate and does not reduce the activity of natural inhibitors; (3) a sufficiently high intake of water and probably other fluids such as coffee, tea, beer and wine has a preventive effect on nephrolithiasis and its recurrence, and (4) the role of fruit juice is still to be defined. Conclusions: A high intake of fluids, especially water, is still the most powerful and certainly the most economical means of prevention of nephrolithiasis, and it is often not used to advantage by stone formers.


  

Author Contacts

Loris Borghi, MD
Istituto di Semeiotica Medica – Università di Parma
Via Gramsci 14, I–43100 Parma (Italy)
Tel. +39 0521 991007, Fax +39 0521 940993
E-Mail lborghi@.ipruniv.cce.unipr.it

  

Article Information

Number of Print Pages : 7
Number of Figures : 1, Number of Tables : 1, Number of References : 51

  

Publication Details

Nephron
Founded 1964 by G. Richet and G.E. Schreiner

Vol. 81, No. Suppl. 1, Year 1999 (Cover Date: Released December 1998)

Journal Editor: G.M. Berlyne, Brooklyn, N.Y.; S. Giovannetti, Pisa
ISSN: 0028–2766 (print), 1423–0186 (Online)

For additional information: http://www.karger.com/journals/nef


Article / Publication Details

First-Page Preview
Abstract of Paper

Published online: 12/24/1998
Issue release date: Released December 1998

Number of Print Pages: 7
Number of Figures: 1
Number of Tables: 1

ISSN: 1660-8151 (Print)
eISSN: 2235-3186 (Online)

For additional information: http://www.karger.com/NEF


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Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in goverment regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
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