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Table of Contents
Vol. 11, No. 3, 2001
Issue release date: April 2001
Section title: Original Paper
Cerebrovasc Dis 2001;11:177–182
(DOI:10.1159/000047635)

Cerebral Vein and Dural Sinus Thrombosis in Portugal: 1980–1998

Ferro J.M. · Correia M. · Pontes C. · Baptista M.V. · Pita F.
Department of Neurology, Hospital Santa Maria, Lisboa, Portugal

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Article / Publication Details

First-Page Preview
Abstract of Original Paper

Published online: 4/6/2001

Number of Print Pages: 6
Number of Figures: 0
Number of Tables: 3

ISSN: 1015-9770 (Print)
eISSN: 1421-9786 (Online)

For additional information: http://www.karger.com/CED

Abstract

There is insufficient information on the prognosis and safety of anticoagulation in acute cerebral vein and dural sinus thrombosis (CVDST). To describe the clinical aspects and medical management of CVDST in Portuguese hospitals, to evaluate the safety of anticoagulation in this setting, and to identify subgroups of CVDST patients with different prognoses, we registered symptomatic CVDST patients admitted to Portuguese hospitals since 1980. Cases were collected from file review up to 6/95 and from consecutively admitted patients from 6/95 to 6/98. One hundred and forty-two patients were included from 20 centers (51 retrospectively and 91 prospectively). One hundred and twelve patients (79%) were anticoagulated. There were only 6 new intracranial hemorrhages (4 in anticoagulated patients) and 2 systemic hemorrhages. Nine (6%) patients died. At discharge, 96 (68%), had recovered completely and only 6 (4%) were dependent (Rankin ≧3). Significant multivariate predictors of death/dependency were central nervous system infection as a predisposing cause (odds ratio, OR = 15.4; 95% confidence interval CI = 111–1.1), encephalopathy on admission (OR = 5.2; 95% CI = 18.7–1.5) and hemorrhage on admission CT/MR (OR = 3.6; 95% CI = 12.9–1). Significant predictors of complete recovery were no encephalopathy on admission (OR = 5; 95% CI = 12.5–2.1), age <45 years (OR = 3.8; 95% CI = 9.2–1.6) and anticoagulation (OR = 3.8; 95% CI = 9.6–1.5). It is possible to identify CVDST patients with potential bad or good prognosis in the acute phase. Anticoagulation was safe and a predictor of complete recovery in acute CVDST.


  

Author Contacts

José M. Ferro, MD, PhD
Centro de Estudos Egas Moniz
Hospital de Santa Maria
P–1649-035 Lisboa (Portugal)
Tel. +351 21 7974956, Fax +351 21 7957474, E-Mail jmferro@ip.pt

  

Article Information

Received: Received: June 25, 2000
Accepted: September 25, 2000
Number of Print Pages : 6
Number of Figures : 0, Number of Tables : 3, Number of References : 26

  

Publication Details

Cerebrovascular Diseases (Official Journal of the European Stroke Council)

Vol. 11, No. 3, Year 2001 (Cover Date: Released April 2001)

Journal Editor: J. Bogousslavsky, Lausanne; M.G. Hennerici, Mannheim
ISSN: 1015–9770 (print), 1421–9786 (Online)

For additional information: http://www.karger.com/journals/ced


Article / Publication Details

First-Page Preview
Abstract of Original Paper

Published online: 4/6/2001

Number of Print Pages: 6
Number of Figures: 0
Number of Tables: 3

ISSN: 1015-9770 (Print)
eISSN: 1421-9786 (Online)

For additional information: http://www.karger.com/CED


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