Measurement of surrogate mast cell-related products in blood or urine is often performed to assess disease extent in evaluating patients with mastocytosis. Serum tryptase and 24-hour urine histamine metabolites are the most commonly used surrogate markers of mastocytosis. In addition, several novel markers including soluble CD117 and soluble CD25 have been identified in recent studies. The utility and the pitfalls of each of these measurements are discussed.
Correspondence to: Dr. Cem Akin
Laboratory of Allergic Diseases NIAID, NIH
10 Center Drive, Room 11C205
Bethesda, MD 20892-1881 (USA)
Tel. +1 301 496 8618, Fax +1 301 480 8384, E-Mail email@example.com
Number of Print Pages : 4
Number of Figures : 0, Number of Tables : 1, Number of References : 21
International Archives of Allergy and Immunology
Vol. 127, No. 2, Year 2002 (Cover Date: February 2002)
Journal Editor: D. Kraft, Vienna
ISSN: 1018–2438 (print), 1423–0097 (Online)
For additional information:http://www.karger.com/journals/iaa
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