Stereotactic Biopsy for Intracranial Space-Occupying Lesions: Clinical Analysis of 550 CasesYu X.a · Liu Z.a · Tian Z.a · Li S.a · Huang H.a · Xiu B.a · Zhao Q.a · Liu L.b · Jing W.b
aDepartment of Neurosurgery, Navy General Hospital of PLA, Beijing, and bDepartment of Neurosurgery, Linfen City Hospital, Shanxi, China
Object: To investigate the role of stereotactic biopsy in planning the optimal management of intracranial space-occupying lesions. Patients and Methods: Between December 1989 and December 1999, stereotactic biopsy was performed in 550 patients with intracranial mass lesions that were deep-seated or located in the functional area. There were 340 males and 210 females, and their ages ranged from 4 to 75 years. All the procedures were done under local anesthesia with a Leksell stereotactic system. A CT scan was used to determine the coordinates in the first 420 cases and the Aero Tech Stereotactic Surgical Plan System in the subsequent 130 patients. Results: Brain tumors were diagnosed pathologically in 475 patients (86.4%), inflammatory process in 44 (8.0%), other lesions in 12 (2.2%) and no conclusive diagnosis was found in 19 (3.4%). The overall positive rate of biopsy was 96.6%, and the positive rate for brain tumor was 86.4%. Intracranial hematomas after biopsy were found in 13 cases (2.4%). Seizures occurred during the operation in 7 cases (1.2%), and slight and transient neurological deficits were found in 23 cases (4.2%). There were no deaths or other serious complications. Conclusions: The results suggest that the stereotactic biopsy is a reliable method to obtain histopathological diagnosis of intracranial mass lesions, and it is also of great help in selecting the appropriate management.
© 2001 S. Karger AG, Basel
Dr. Xin Yu
Department of Neurosurgery, Navy General Hospital
6 Fucheng Road, Beijing, 100037 (China)
Tel. +86 10 68579677, Fax +86 10 68530645
Number of Print Pages : 6
Number of Figures : 0, Number of Tables : 2, Number of References : 14
Stereotactic and Functional Neurosurgery (Official Journal of the World Society for Stereotactic and Functional Neurosurgery; Official Journal of the American Society for Stereotactic and Functional Neurosurgery)
Founded 1938 as ‘Confinia Neurologica’ by E.A. Spiegel; Continued 1975–1988 as ‘Applied Neurophysiology’
Vol. 75, No. 2-3, Year 2000 (Cover Date: Released December 2001)
Journal Editor: Ph.L. Gildenberg, Houston, Tex.
ISSN: 1011–6125 (print), 1423–0372 (Online)
For additional information: http://www.karger.ch/journals/sfn