In 1992, the twelve-item Brief Smell Identification Test® and, in 1992 and 1996, a variety of measures of verbal learning and memory, executive control, and global function were administered to a total of 359 individuals (286 men and 73 women; mean age in 1992 74.3 years). Individuals with a history of stroke or impaired cognition at baseline were excluded from analyses. Impaired olfactory function (present or absent) was related to a greater 4.5-year decline on several indices of verbal memory, but not to a decline on measures of executive control or of global functioning after adjustment for baseline cognitive performance, age, education, gender, and history of smell difficulties. Olfactory loss remained associated with a decline in components of verbal memory, independently of the apolipoprotein E ε4 status. The predictive utility of impaired smell identification in older adults appears to be specific to a decline in components of verbal memory.
© 2002 S. Karger AG, Basel
Gary E. Swan, PhD
Center for Health Sciences, SRI International
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Number of Print Pages : 10
Number of Figures : 0, Number of Tables : 5, Number of References : 64
Founded 1982 by B.S. Schoenberg, continued by M. Alter (1989–1996)
Vol. 21, No. 2, Year 2002 (Cover Date: March-April 2002)
Journal Editor: G.C. Román, San Antonio, Tex.
ISSN: 0251–5350 (print), 1423–0208 (Online)
For additional information: http://www.karger.com/journals/ned
Article / Publication Details
Published online: 3/15/2002
Issue release date: March–April 2002
Number of Print Pages: 10
Number of Figures: 0
Number of Tables: 5
ISSN: 0251-5350 (Print)
eISSN: 1423-0208 (Online)
For additional information: http://www.karger.com/NED
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