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Vol. 13, No. 1, 2002
Issue release date: December 2001
Section title: Original Research Article
Dement Geriatr Cogn Disord 2002;13:13–20
(DOI:10.1159/000048628)

The Hopkins Verbal Learning Test and Screening for Dementia

Hogervorst E.a · Combrinck M.a · Lapuerta P.b · Rue J.a · Swales K.a · Budge M.a
aUniversity of Oxford, Oxford Project to Investigate Memory and Ageing (OPTIMA), Oxford, UK, bPharmaceutical Research Institute, Bristol-Myers Squibb, Princeton, N.Y., and Robert Wood Medical School, New Brunswick, N.J., USA

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Article / Publication Details

First-Page Preview
Abstract of Original Research Article

Published online: 12/5/2001
Issue release date: December 2001

Number of Print Pages: 8
Number of Figures: 4
Number of Tables: 2

ISSN: 1420-8008 (Print)
eISSN: 1421-9824 (Online)

For additional information: http://www.karger.com/DEM

Abstract

The present study investigated the sensitivity and specificity of the Hopkins Verbal Learning Test (HVLT) for demented patients (n = 82, using NINCDS criteria) and 114 healthy controls – equivalent in age, years of education and gender-ratio – from the Oxford Project to Investigate Memory and Ageing. The HVLT ‘Total Recall’ score had 87% sensitivity and 98% specificity for dementia using a cut-off score of 14.5. Using a ‘Memory’ score (the sum of the ‘Total Recall’ and the ‘Discrimination Index’) with a cut-off score of 24.5 gave a 91% sensitivity and 98% specificity for Alzheimer’s disease cases when compared to controls. Unlike the MMSE, the HVLT has no ceiling effects and does not have to be adjusted for education. We conclude that the HVLT is an easy to administer, quick and well tolerated tool for the screening of dementia.

© 2002 S. Karger AG, Basel


  

Author Contacts

Dr. Eva Hogervorst
Oxford Project to Investigate Memory and Ageing
University of Oxford and Radcliffe Infirmary Trust
Woodstock Road, Oxford, OX2 6HE (UK)
Tel. +44 1865 228512, Fax +44 1865 224099, E-Mail eva.hogervorst@pharm.ox.ac.uk

  

Article Information

Received: Accepted: February 28, 2001
Number of Print Pages : 8
Number of Figures : 4, Number of Tables : 2, Number of References : 22

  

Publication Details

Dementia and Geriatric Cognitive Disorders

Vol. 13, No. 1, Year 2002 (Cover Date: Released December 2001)

Journal Editor: V. Chan-Palay, New York, N.Y.
ISSN: 1420–8008 (print), 1421–9824 (Online)

For additional information: http://www.karger.com/journals/dem


Article / Publication Details

First-Page Preview
Abstract of Original Research Article

Published online: 12/5/2001
Issue release date: December 2001

Number of Print Pages: 8
Number of Figures: 4
Number of Tables: 2

ISSN: 1420-8008 (Print)
eISSN: 1421-9824 (Online)

For additional information: http://www.karger.com/DEM


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Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in goverment regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
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