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Vol. 13, Suppl. 2, 2002
Issue release date: 2002
Section title: Paper
Cerebrovasc Dis 2002;13(suppl 2):58–60
(DOI:10.1159/000049152)

Subcortical Vascular Dementia

Erkinjuntti T.
Memory Research Unit, Department of Clinical Neurosciences, University of Helsinki, Finland

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Article / Publication Details

First-Page Preview
Abstract of Paper

Published online: 3/15/2002

Number of Print Pages: 3
Number of Figures: 0
Number of Tables: 2

ISSN: 1015-9770 (Print)
eISSN: 1421-9786 (Online)

For additional information: http://www.karger.com/CED

Abstract

Vascular dementia (VaD) incorporates different vascular mechanisms and changes in the brain, and has different causes and clinical manifestations. Current criteria for VaD select an aetiologically and clinically heterogeneous group and this definitional heterogeneity has affected clinical trial results. Focus on a more homogeneous group, such as that with subcortical (ischaemic) VaD, could be an alternative in clinical drug trials. This subtype incorporates two small vessel clinical entities – ‘Binswanger’s disease’ and ‘the lacunar state’. It comprises small vessel disease as the primary vascular aetiology, lacunar infarct(s) and ischaemic white matter lesions as the primary type of brain lesions, subcortical location as the primary location of lesions, and the subcortical clinical syndrome as the primary clinical manifestation. Subcortical VaD is expected to show a more predictable clinical picture, natural history, outcome and treatment responses.


  

Author Contacts

Timo Erkinjuntti, MD, PhD
Memory Research Unit, Department of Clinical Neurosciences
Helsinki University Central Hospital
PO Box 300, FIN–00290 Hyks (Finland)
Tel. +358 9 471 7 2353, Fax +358 9 471 7 5550, E-Mail timo.erkinjuntti@huch.fi

  

Article Information

Number of Print Pages : 3
Number of Figures : 0, Number of Tables : 2, Number of References : 27

  

Publication Details

Cerebrovascular Diseases (Official Journal of the European Stroke Council)

Vol. 13, No. Suppl. 2, Year 2002 (Cover Date: Released March 2002)

Journal Editor: J. Bogousslavsky, Lausanne; M.G. Hennerici, Mannheim
ISSN: 1015–9770 (print), 1421–9786 (Online)

For additional information: http://www.karger.com/journals/ced


Article / Publication Details

First-Page Preview
Abstract of Paper

Published online: 3/15/2002

Number of Print Pages: 3
Number of Figures: 0
Number of Tables: 2

ISSN: 1015-9770 (Print)
eISSN: 1421-9786 (Online)

For additional information: http://www.karger.com/CED


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Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in goverment regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
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