Pulmonary Tuberculosis in Patients with Diabetes mellitusBacakoğlu F. · Başoğlu Ö. · Çok G. · Sayıner A. · Ateş M.
Department of Chest Diseases, Ege University Medical School, Izmir, Turkey
Background: Diabetes mellitus has been reported to modify the presenting features of pulmonary tuberculosis, but there are varying data, particularly regarding the association with lower lung field involvement. Objectives: To determine whether diabetes mellitus alters the clinical and radiographic manifestations of tuberculosis in nonimmunocompromised hosts and to define the determinants of lower lung field involvement. Methods: A retrospective review of the records of all patients with tuberculosis and diabetes mellitus seen during a 14-year period and of an age- and sex-matched nondiabetic control group with tuberculosis was carried out. The duration of symptoms, tuberculin reaction, bacteriologic and radiographic findings of the two groups were compared. Results: The presence of diabetes mellitus was found not to have an effect on patients’ symptomatology, bacteriology results, tuberculin reaction and localization of pulmonary infiltrates. On the other hand, fewer diabetic patients were smear-positive and fewer had reticulonodular opacities compared with the control patients. A higher number of insulin-dependent diabetic patients presented with cavitary disease as compared with nondiabetic controls. Lower lung field tuberculosis was significantly associated with female gender and, in patients older than 40 years, was more frequently observed in diabetics. Conclusion: These data show that diabetes does not affect the presenting features of pulmonary tuberculosis to a large extent and is only associated with lower lung field disease in older patients.
Dr. Abdullah Sayıner
Ege Üniversitesi Tıp Fakültesi Göğüs Hastalıkları A.D.
TR–35100 Bornova, Izmir (Turkey)
Tel. +90 232 388 1423, Fax +90 232 388 7192, E-Mail firstname.lastname@example.org
Received: Received: November 13, 2000
Accepted after revision: April 24, 2001
Number of Print Pages : 6
Number of Figures : 0, Number of Tables : 7, Number of References : 24
Respiration (International Review of Thoracic Diseases)
Founded 1944 as ‘Schweizerische Zeitschrift für Tuberkulose und Pneumonologie’ by E. Bachmann, M. Gilbert, F. Häberlin, W. Löffler, P. Steiner and E. Uehlinger, continued 1962–1967 as ‘Medicina Thoracalis’
Vol. 68, No. 6, Year 2001 (Cover Date: November-December 2001)
Journal Editor: C.T. Bolliger, Cape Town
ISSN: 0025–7931 (print), 1423–0356 (Online)
For additional information: http://www.karger.com/journals/res