Maintenance Electroconvulsive Therapy in Affective and Schizoaffective DisorderSwoboda E. · Conca A. · König P. · Waanders R. · Hansen M.
Department of Psychiatry I, Landeskrankenhaus Rankweil, Austria
Twenty-one patients (13 depressives and 8 schizoaffectives) who underwent maintenance electroconvulsive therapy (M-ECT) were compared with controls who received maintenance pharmacotherapy alone. Measures of effectiveness and safety of maintenance treatment were prospectively obtained during a 1-year follow-up. Survival analysis demonstrated a significantly better outcome defined by time to rehospitalization for all patients of the M-ECT group. Regarding the subgroups, depressives of the M-ECT group had markedly decreased rehospitalization rates cmpared to depressive controls. Furthermore, M-ECT in depressives resulted in a significant reduction in hospitalization rates and duration during follow-up. In schizoaffective patients, a significant difference in survival time was found in favor of the M-ECT group. In both groups, schizoaffectives had a markedly poorer outcome compared to depressive subjects. Our results indicate that in selected patients M-ECT, at least in combination with supporting medication, may be an efficient and safe alternative to pharmacological continuation or maintenance therapy alone.
Dr. E. Swoboda
Department of Psychiatry I, Landeskrankenhaus Rankweil
A–6830 Rankweil (Austria)
Tel. +43 5522 403 254, Fax +43 5522 403 355
Number of Print Pages : 6
Number of Figures : 2, Number of Tables : 3, Number of References : 28
Neuropsychobiology (International Journal of Experimental and Clinical Research in Biological Psychiatry, Pharmacopsychiatry, Biological Psychology/Pharmacopsychology and Pharmacoelectroencephalography)
Founded 1975 by J. Mendlewicz (Brussels)
Official Journal of the International Pharmaco-EEG Society (IPEG)
Vol. 43, No. 1, Year 2001 (Cover Date: Released January 2001)
Journal Editor: J. Mendlewicz, Brussels; B. Saletu, Vienna; P. Netter, Giessen; W.M. Herrmann, Berlin
ISSN: 0302–282X (print), 1423–0224 (Online)
For additional information: http://www.karger.com/journals/nps