Natural Course of Chronic PancreatitisLankisch P.G.
Department of Internal Medicine, Municipal Clinic of Lüneburg, Germany
Although the three leading symptoms of chronic pancreatitis, pain, exocrine and endocrine pancreatic insufficiency, are well known, only a few long-term studies have correlated these symptoms with the natural course of the disease. Besides these symptoms, numerous pancreatic complications and/or pancreatitis-associated diseases may affect the course and determine the prognosis of chronic pancreatitis. Their influence, however, has not been studied in detail. This review has two major aims: The first one is to give an up-to-date survey of present knowledge on the natural course of the disease with a view to the leading symptoms under special consideration of how the duration of the disease, continual alcohol abuse as well as endoscopic procedures and surgical treatment affect pain. Included is also what is known about chronic pancreatitis as a precondition of pancreatic and extrapancreatic carcinoma. The effect of chronic pancreatitis on the socio-economic status of patients is discussed and the mortality rate of the disease. The second aim of this review is to stimulate pancreatologists from different centers to consolidate resources in order to perform larger controlled studies than any one single center can undertake and work out common criteria for the diagnosis of chronic pancreatitis and follow-up of its course.
P.G. Lankisch, MD
Medizinische Klinik, Städtisches Klinikum Lüneburg
D–21339 Lüneburg (Germany)
Tel. +49 4131 77 2240, Fax +49 4131 77 2245, E-Mail firstname.lastname@example.org
Based on a lecture at the combined meeting of the International Association of Pancreatology and the American Pancreatic Association, Chicago, 2000.
Number of Print Pages : 12
Number of Figures : 2, Number of Tables : 8, Number of References : 102
Official Publication of the International Association of Pancreatology (IAP); Official Publication of the European Pancreatic Club (EPC); Official Publication of the Spanish Pancreatic Club; Official Publication of the Club Português do Pancreas; Official Publication of the Pancreatic Society of Great Britain and Ireland; Official Publication of the Associazione Italiana per lo Studio del Pancreas
Vol. 1, No. 1, Year 2001 (Cover Date: 2001)Formerly International Journal of Pancreatology
Journal Editor: Manfred V. Singer, Mannheim; Clem W. Imrie, Glasgow
ISSN: 1424–3903 (print), 1424–3911 (Online)
For additional information: http://www.karger.com/journals/pan