Accuracy of Endoscopic Ultrasound in Diagnosing and Staging Pancreatic CarcinomaWiersema M.J.
Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minn., USA
Background: The role of endosonography in diagnosing and staging pancreatic adenocarcinoma is evolving. The aim of this review is to present recently published material comparing the performance of endosonography relative to other imaging modalities when evaluating a patient with a suspected or known carcinoma of the pancreas. Methods: Medline was searched using the terms ‘endosonography’ and ‘pancreas neoplasms’. References from retrieved papers were reviewed to identify other reports. Emphasis was placed on peer-reviewed material published within the past 3 years that included comparison with other imaging modalities. Results: Despite advances in cross-sectional imaging modalities, endosonography remains the most sensitive and specific method to identify pancreatic mass lesions. Resectability determination of pancreatic carcinoma is best done with dual-phase helical CT, although endosonography may have slightly improved accuracy for lymph node assessment. Endosonography-guided fine-needle aspiration biopsy has high sensitivity (93%) and specificity (100%) when employed in patients with masses in whom pancreatic cancer is suspected but prior biopsies are negative. Conclusions: Endosonography can aid in diagnosing patients with pancreatic neoplasms through definitive inclusion or exclusion of a mass lesion as well as biopsy confirmation of malignancy. The role of endosonography in determination of resectability has been eclipsed by dual-phase helical CT.
Maurits J. Wiersema, MD
Eisenberg 8A, Mayo Clinic
200 First Street, SW
Rochester, MN 55905 (USA)
Tel. +1 507 266 6931, Fax +1 507 266 3939, E-Mail firstname.lastname@example.org
Number of Print Pages : 8
Number of Figures : 2, Number of Tables : 4, Number of References : 35
Official Publication of the International Association of Pancreatology (IAP); Official Publication of the European Pancreatic Club (EPC); Official Publication of the Spanish Pancreatic Club; Official Publication of the Club Português do Pancreas; Official Publication of the Pancreatic Society of Great Britain and Ireland; Official Publication of the Associazione Italiana per lo Studio del Pancreas
Vol. 1, No. 6, Year 2001 (Cover Date: 2001)Formerly International Journal of Pancreatology
Journal Editor: Manfred V. Singer, Mannheim; Clem W. Imrie, Glasgow
ISSN: 1424–3903 (print), 1424–3911 (Online)
For additional information: http://www.karger.com/journals/pan