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Vol. 14, No. 4, 2001
Issue release date: July–August 2001
Section title: Review
Skin Pharmacol Appl Skin Physiol 2001;14:183–195
(DOI:10.1159/000056346)

Assessment of ‘Dry Skin’: Current Bioengineering Methodsa nd Test Designs

Fischer T.W. · Wigger-Alberti W. · Elsner P.
Department of Dermatology, Friedrich Schiller University, Jena, Germany

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Article / Publication Details

First-Page Preview
Abstract of Review

Published online: 7/19/2001

Number of Print Pages: 13
Number of Figures: 0
Number of Tables: 0

ISSN: 1660-5527 (Print)
eISSN: 1660-5535 (Online)

For additional information: http://www.karger.com/SPP

Abstract

Dry skin is a frequent problem in dermatology and a sign of dysfunction of the epidermis, especially of the stratum corneum as the morphological equivalent of the skin barrier. It may occur as an individual disposition or as the leading symptom of atopic dermatitis or ichthyosis. Besides the visual examination of the skin, various bioengineering methods have been developed to assess the different pathological and adaptive changes in the skin. In addition to the assessment of skin humidity, barrier function and desquamation, the quantification of skin surface topography and the mechanical properties of skin are suitable methods to characterize a dry skin condition. For clinical assessment of moisturizing products and emollients the parameters of investigation have to be defined and integrated in an adapted study design depending on the composition and content of the active agent in the test product. Newly developed cosmetic products have to be investigated for safety and efficacy. Modern bioengineering methods are suitable to fulfill these challenges.


  

Author Contacts

Dr. Tobias W. Fischer
Department of Dermatology, Friedrich Schiller University Jena
Erfurter Strasse 35, D–07740 Jena (Germany)
Tel. +49 3641 937328, Fax +49 3641 937430
E-Mail Tobias.Fischer@derma.uni-jena.de

  

Article Information

Received: Received: June 16, 1999
Accepted: Nov. 30, 2000
Number of Print Pages : 13
Number of Figures : 0, Number of Tables : 0, Number of References : 56

  

Publication Details

Skin Pharmacology and Applied Skin Physiology (Journal of Pharmacological and Biophysical Research)
Incorporating ‘Bioengineering and the Skin’; Founded in 1988 by H. Schaefer
Official Journal of the Skin Pharmacology Society (SPS)

Vol. 14, No. 4, Year 2001 (Cover Date: July-August 2001)

Journal Editor: Hans F. Merk, Aachen
ISSN: 1422–2868 (print), 1422–2906 (Online)

For additional information: http://www.karger.com/journals/sph


Article / Publication Details

First-Page Preview
Abstract of Review

Published online: 7/19/2001

Number of Print Pages: 13
Number of Figures: 0
Number of Tables: 0

ISSN: 1660-5527 (Print)
eISSN: 1660-5535 (Online)

For additional information: http://www.karger.com/SPP


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Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in goverment regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
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