Several theories have been proposed to explain the often-noted sterility of both reciprocal and Robertsonian X-autosome translocations in male mammals. However, there are a number of species in which all members of the species carry a Robertsonian X-autosome translocation. Meiosis in spermatocytes from these sterile vs. fertile animals is compared within the context of these theories. New technologies and insights into underlying mechanisms are summarized and suggestions presented for further studies.
© 2002 S. Karger AG, Basel
Request reprints from Terry Ashley, Department of Genetics
Yale University School of Medicine, 333 Cedar Street
New Haven CT 06510 (USA); telephone: 203-785-4473
fax: 203-785-4958; e-mail: Terry.Ashley@yale.edu
This article is dedicated to Professor Karl Fredga to commemorate his retirement and lifelong cytogenetic research activities.
Supported by grants from the National Institutes of Health (GM 47797 and GM 55300).
Received: Received 7 February 2002;
manuscript accepted 13 March 2002.
Number of Print Pages : 7
Number of Figures : 0, Number of Tables : 1, Number of References : 59
Cytogenetic and Genome Research
Formerly ‘Cytogenetics and Cell Genetics’
Vol. 96, No. 1-4, Year 2002 (Cover Date: 2002)
Journal Editor: H.P. Klinger, Bronx, N.Y.; M. Schmid, Würzburg
ISSN: 1424–8581 (print), 1424–859X (Online)
For additional information: http://www.karger.com/journals/cgr
Article / Publication Details
Published online: 8/26/2002
Issue release date: 2002
Number of Print Pages: 7
Number of Figures: 0
Number of Tables: 1
ISSN: 1424-8581 (Print)
eISSN: 1424-859X (Online)
For additional information: http://www.karger.com/CGR
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