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Vol. 69, No. 5, 2002
Issue release date: September–October 2002
Section title: Case Report
Respiration 2002;69:468–470
(DOI:10.1159/000064013)

Necrotizing Sarcoid Granulomatosis Presenting with Elevated Serum Soluble Interleukin-2 Receptor Levels

Harada T. · Amano T. · Takahashi A. · Furuya J. · Yamaguchi E. · Kaji M. · Morikawa T. · Itoh T. · Shimizu M. · Nishimura M.
aFirst Department of Medicine, bSecond Department of Surgery, Hokkaido University School of Medicine, and cDepartment of Surgical Pathology, Hokkaido University Hospital, Sapporo, Japan

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Article / Publication Details

First-Page Preview
Abstract of Case Report

Received: 2/4/2001
Accepted: 8/7/2001
Published online: 9/9/2002

Number of Print Pages: 3
Number of Figures: 2
Number of Tables: 0

ISSN: 0025-7931 (Print)
eISSN: 1423-0356 (Online)

For additional information: http://www.karger.com/RES

Abstract

A 52-year-old woman presented with a one-week history of low-grade fever and dyspnea. A CT scan showed multiple pulmonary nodules with cavitation, as well as bilateral pleural thickenings with effusions. A specimen resected by video-assisted thoracoscopic surgery showed multiple confluent granulomas with central necrosis and granulomatous vasculitis. These findings were consistent with necrotizing sarcoid granulomatosis. An elevated serum soluble interleukin-2 receptor level became normal following clinical and radiological improvement. This indicates that the serum soluble interleukin-2 receptor can be a useful marker for the clinical management of necrotizing sarcoid granulomatosis.


  

Author Contacts

Toshiyuki Harada
First Department of Medicine, Hokkaido University School of Medicine
North 15, West 7, Kita-ku, Sapporo, 060-8638 (Japan)
Tel. +81 11 7161161, ext. 5911, Fax +81 11 7067899, E-Mail t-harada@med.hokudai.ac.jp

  

Article Information

Received: Received: August 7, 2001
Accepted after revision: February 4, 2002
Number of Print Pages : 3
Number of Figures : 2, Number of Tables : 0, Number of References : 7

  

Publication Details

Respiration (International Review of Thoracic Diseases)
Founded 1944 as ‘Schweizerische Zeitschrift für Tuberkulose und Pneumonologie’ by E. Bachmann, M. Gilbert, F. Häberlin, W. Löffler, P. Steiner and E. Uehlinger, continued 1962–1967 as ‘Medicina Thoracalis’ as of 1968 as ‘Respiration’, H. Herzog (1962–1997)
Official Journal of the European Association for Bronchology and Interventional Pulmonology

Vol. 69, No. 5, Year 2002 (Cover Date: September-October 2002)

Journal Editor: C.T. Bolliger, Cape Town
ISSN: 0025–7931 (print), 1423–0356 (Online)

For additional information: http://www.karger.com/journals/res


Article / Publication Details

First-Page Preview
Abstract of Case Report

Received: 2/4/2001
Accepted: 8/7/2001
Published online: 9/9/2002

Number of Print Pages: 3
Number of Figures: 2
Number of Tables: 0

ISSN: 0025-7931 (Print)
eISSN: 1423-0356 (Online)

For additional information: http://www.karger.com/RES


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