Epidemiological Perspectives for the Development of Future Diagnostic SystemsKessler R.C.
Department of Health Care Policy, Harvard Medical School, Boston, Mass., USA
Three uses of epidemiological data for diagnostic revisions are suggested. (1) Psychometric analysis of community cases over the full spectrum of symptom severity can help determine whether true discrete disease entities underlie particular symptom profiles. (2) Analysis of external validators in community samples can help select optimal cut-points for defining diagnostic criteria. (3) Clinical epidemiological studies can provide quick and comparatively inexpensive preliminary checks, prior to carrying out expensive experimental treatment trials, on the plausibility of proposed subtyping distinctions based on nonexperimental evidence regarding differential treatment response. Correction of a number of basic conceptual and methodological flaws that have hampered previous studies would allow epidemiological research of these three sorts to play a much more important part in future diagnostic revisions than they have in past revisions.
Prof. Ronald C. Kessler
Department of Health Care Policy, Harvard Medical School
180 Longwood Avenue, Suite 215
Boston, MA 02115 (USA)
Tel. +1 617 432 3333, Fax +1 617 432 3588, E-Mail email@example.com
Number of Print Pages : 4
Number of Figures : 0, Number of Tables : 0, Number of References : 16
Psychopathology (International Journal of Descriptive Psychopathology Phenomenology and Clinical Diagnositcs)
Founded 1897 as ‘Monatsschrift für Psychiatrie und Neurologie’
Vol. 35, No. 2-3, Year 2002 (Cover Date: March-June 2002)
Journal Editor: E. Gabriel, Vienna; C. Mundt, Heidelberg
ISSN: 0254–4962 (print), 1423–033X (Online)
For additional information: http://www.karger.com/journals/psp