Complications following Acute Ischemic StrokeWeimar C. · Roth M.P. · Zillessen G. · Glahn J. · Wimmer M.L.J. · Busse O. · Haberl R.L. · Diener H.C. · on behalf of the German Stroke Data Bank Collaborators O.
Departments of Neurology,aUniversity of Essen, Essen, bUniversity of Homburg, Homburg, cUniversity of Greifswald, Greifswald, dKlinikum Minden, Minden, and eKrankenhaus München-Harlaching, München, Germany
The objective of this study was to assess typical early-onset complications following ischemic stroke in a large, hospital-based cohort to provide clinical data for future randomized trials and quality standards in clinical routine. 3,866 patients with acute ischemic stroke were prospectively documented in 14 Neurology Departments with an acute stroke unit. Within the first week after admission, increased intracranial pressure (7.6%) and recurrent cerebral ischemia (5.1%) were the most frequent neurological complications. Fever >38°C (13.2%), severe arterial hypertension (7.5%) and pneumonia (7.4%) were the most frequent medical complications. Multivariate regression analysis yielded brain stem infarction and large-artery atherosclerosis as independent predictors for early recurrent ischemic stroke. This study provides representative data on onset and severity of early neurological and medical complications as well as possible predictors for early recurrent cerebral ischemia following acute ischemic stroke.
Dr. Christian Weimar
Department of Neurology, University of Essen
Hufelandstrasse 55, D–45122 Essen (Germany)
Tel. +49 201 723 2171, Fax +49 201 723 5753
Received: Received: December 10, 2001
Accepted: May 7, 2002
Number of Print Pages : 8
Number of Figures : 2, Number of Tables : 4, Number of References : 30
Founded 1897 as ‘Monatsschrift für Psychiatrie und Neurologie’
Vol. 48, No. 3, Year 2002 (Cover Date: Released October 2002)
Journal Editor: J. Bogousslavsky, Lausanne
ISSN: 0014–3022 (print), 1421–9913 (Online)
For additional information: http://www.karger.com/journals/ene