Two-Peak Temporal Distribution of Stroke Onset in Greek Patients
A Hospital-Based StudySpengos K. · Vemmos K.N. · Tsivgoulis G. · Synetos A. · Zakopoulos N.A. · Zis V.P. · Vassilopoulos D.
Departments of aNeurology, University of Athens School of Medicine, ‘Eginition’ Hospital and bClinical Therapeutics, University of Athens School of Medicine, ‘Alexandra’ Hospital, Athens, Greece
A circadian distribution with a single peak of stroke onset in the morning hours has been described in various countries. Analysis of the temporal pattern of symptom onset in a series of 1,253 Greek first-ever stroke patients revealed a circadian distribution with two incidence peaks between 08.00 and 10.00 h, and between 16.00 and 18.00 h. Considering the different etiopathogenic types of stroke, the same two-peak time pattern was evaluated in all stroke subgroups with the only exception of lacunar stroke, which seems to predominantly occur during night and sleep. A secondary stroke onset peak in the late afternoon has not been previously described in such detail. A relation between the second, however lower, frequency peak and the traditional Greek habit of afternoon sleep (siesta) could be assumed and deserves further investigation.
Konstantinos Spengos, MD
Vasilissis Sofias Ave 82
GR–11528 Athens (Greece)
Tel. +30 946 466216, Fax +30 10 7780222
Received: Received: February 8, 2002
Accepted: May 10, 2002
Number of Figures : 4, Number of Tables : 2, Number of References : 35
Cerebrovascular Diseases (Official Journal of the European Stroke Council)
Vol. 15, No. 1-2, Year 2003 (Cover Date: Released January 2003)
Journal Editor: J. Bogousslavsky, Lausanne; M.G. Hennerici, Mannheim
ISSN: 1015–9770 (print), 1421–9786 (Online)
For additional information: http://www.karger.com/journals/ced