History of Fetal Diagnosis and Therapy: Children’s Hospital of Philadelphia ExperienceHedrick H.L. · Flake A.W. · Crombleholme T.M. · Howell L.J. · Johnson M.P. · Wilson R.D. · Adzick N.S.
Center for Fetal Diagnosis and Treatment, Children’s Hospital of Philadelphia, and Department of Surgery and Obstetrics and Gynecology, University of Pennsylvania School of Medicine, Philadelphia, Pa., USA
Since its inception in 1995, the mission of the Center for Fetal Diagnosis and Treatment at the Children’s Hospital of Philadelphia (CHOP) has been to provide comprehensive, multidisciplinary expertise in all facets of prenatal diagnosis, reproductive genetics, and prenatal, perinatal, and postnatal treatment for abnormal fetuses. Most of the authors were trained and/or served on faculty at centers in San Francisco (N.S.A., A.W.F., T.M.C., L.J.H.) or Detroit (A.W.F, M.P.J.). Accurate prenatal detection by serial sonographic study and the development of ultrafast magnetic resonance imaging (MRI) scanners has permitted delineation of the natural history of anatomic malformations. Definition of the pathophysiological features that affect clinical outcome and formulation of management based on prognosis has allowed families to make informed decisions. Outcomes have been improved through carefully planned and coordinated perinatal management. In some cases of life-threatening or severely debilitating defects, prenatal surgery has been offered.
N. Scott Adzick, MD
Center for Fetal Diagnosis and Treatment
Children’s Hospital of Philadelphia, 34th Street and Civic Center Boulevard
Philadelphia, PA 19104 (USA)
Tel. +1 215 590 2727, E-Mail email@example.com
Number of Figures : 8, Number of Tables : 3, Number of References : 120
Fetal Diagnosis and Therapy (Clinical Advances and Basic Research)
Formerly ‘Fetal Therapy’
Official Organ of the ‘International Fetal Medicine and Surgery Society’ and ‘Fetus as a Patient’
Vol. 18, No. 2, Year 2003 (Cover Date: March-April 2003)
Journal Editor: W. Holzgreve, Basel; D. Surbek, Basel; M. Michejda, Washington, D.C.; K.C. Pringle, Wellington; M.I. Evans, New York, N.Y.; H. Nakano, Fukuoka; S. Uzan, Paris
ISSN: 1015–3837 (print), 1421–9964 (Online)
For additional information: http://www.karger.com/fdt