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Vol. 91, No. 4, 1999
Issue release date: October 1999
Section title: Case Report
Cardiology 1999;91:268–271
(DOI:10.1159/000006922)

Bradycardia, Reversible Panconduction Defect and Syncope following Self-Medication with a Homeopathic Medicine

Guha S. · Dawn B. · Dutta G. · Chakraborty T. · Pain S.
aDivision of Cardiology, Department of Medicine, Calcutta Medical College, Calcutta, India; bDivision of Cardiology, Department of Medicine, University of Louisville, Louisville, Ky., USA

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Article / Publication Details

First-Page Preview
Abstract of Case Report

Published online: 10/25/1999

Number of Print Pages: 4
Number of Figures: 1
Number of Tables: 0

ISSN: 0008-6312 (Print)
eISSN: 1421-9751 (Online)

For additional information: http://www.karger.com/CRD

Abstract

Alkaloid extracts from the plant Aconitum species have been used in various forms of herbal remedies predominantly as anti-inflammatory and analgesic agents. Many of these alkaloids are extremely potent cardiotoxins and documented cases of various arrhythmias with fatal outcomes have been reported. We report a case of self-medication with ‘tincture of aconite’ resulting in severe bradycardia, reversible panconduction defect evidenced by sinus inactivity, atrioventricular dissociation with idiojunctional rhythm and left bundle branch block pattern resulting in hypotension and syncope. Complete reversal of ECG findings with marked improvement in symptoms was noted within a few hours. Herbal medicines containing aconite alkaloids may result in severe cardiotoxicity, and strict regulatory measures are warranted to curb unsupervised use for therapeutic purposes.


  

Author Contacts

Buddhadeb Dawn, MD
Division of Cardiology, University of Louisville, Ambulatory Care Building, 3rd Floor
550 South Jackson Street
Louisville, KY 40292 (USA)
Tel. +1 502 852 7959, Fax +1 502 852 7147, E-Mail b0dawn01@athena.louisville.edu

  

Article Information

Received: Received: March 31, 1999
Accepted: April 8, 1999
Number of Print Pages : 4
Number of Figures : 1, Number of Tables : 0, Number of References : 12

  

Publication Details

Cardiology (International Journal of Cardiovascular Medicine, Surgery andPathology)
Founded 1937 as ‘Cardiologia’ by Bruno Kisch and WilhelmLöffler

Vol. 91, No. 4, Year 1999 (Cover Date: Released October 1999)

Journal Editor: Joseph S. Alpert, Tucson, Ariz.
ISSN: 0008–6312 (print), 1421–9751 (Online)

For additional information:http://www.karger.com/journals/crd


Article / Publication Details

First-Page Preview
Abstract of Case Report

Published online: 10/25/1999

Number of Print Pages: 4
Number of Figures: 1
Number of Tables: 0

ISSN: 0008-6312 (Print)
eISSN: 1421-9751 (Online)

For additional information: http://www.karger.com/CRD


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Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher or, in the case of photocopying, direct payment of a specified fee to the Copyright Clearance Center.
Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in goverment regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
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