Primary Cutaneous CD30+ Large T-Cell Lymphoma in a Patient with Psoriasis Treated with CyclosporineCorazza M. · Zampino M.R. · Montanari A. · Altieri E. · Virgili A.
Dipartimento di Medicina Clinica e Sperimentale, Sezione di Dermatologia, Università di Ferrara, Ferrara, Italy
We report the case of a 61-year-old woman who developed an anaplastic CD30+ cutaneous T-cell lymphoma during oral cyclosporine (CsA) therapy for recalcitrant psoriasis. Two months after CsA discontinuation, clinical and histological resolution of the lymphoma was observed. However, 3 years later extracutaneous involvement of the lymphoma could be detected. The association between CsA administration and the occurrence of the lymphoma may be casual, but a relationship with immunosuppression may also be hypothesized. We have reviewed all relevant data in the literature. To our knowledge, this is the first case of primary cutaneous CD30+ anaplastic large T-cell lymphoma in a patient treated with CsA for psoriasis.
© 2003 S. Karger AG, Basel
Dr. M. Corazza
Dipartimento di Medicina Clinica e Sperimentale – Sezione di Dermatologia
Università di Ferrara, Via Savonarola 9
I–44100 Ferrara (Italy)
Tel. +39 0532 236308, Fax +39 0532 206791, E-Mail email@example.com
Received: April 25, 2002
Accepted: October 11, 2002
Number of Print Pages : 4
Number of Figures : 3, Number of Tables : 0, Number of References : 21
Dermatology (International Journal for Clinical and Investigative Dermatology)
Founded as ‘Dermatologische Zeitschrift’ by Oskar Lassar (1893–1907); Continued by Erich Hoffmann (1908–1938), continued as ‘Dermatologica’ (1939–1991), by Wilhelm Lutz (1939–1958), Rudolf Schuppli (1959–1985)
Official Organ of the Swiss Society for Dermatology and Venereology; Official Organ of the Belgian Royal Society for Dermatology and Venereology
Vol. 206, No. 4, Year 2003 (Cover Date: 2003)
Journal Editor: J.-H. Saurat, Geneva.
ISSN: 1018–8665 (print), 1421–9832 (Online)
For additional information: http://www.karger.com/journals/drm