Management of Drug Rash with Eosinophilia and Systemic Symptoms (DRESS Syndrome): An UpdateTas S. · Simonart T.
Department of Dermatology, Erasme University Hospital, Brussels, Belgium
Drug rash with eosinophilia and systemic symptoms (DRESS) syndrome is a rather distinct severe adverse drug reaction characterised by skin rash, fever, lymph node enlargement and internal organ involvement. Our aim was to review the available data regarding the management of this probably underrecognised subset of drug reaction. So far, the only undisputed way to treat severe hypersensitivity reactions is prompt withdrawal of the offending drug. The use of systemic corticosteroids remains controversial. The benefit of therapies aimed at accelerating the elimination of the causative drug deserves further studies. In the absence of a well-established therapy, primary and secondary prevention have a key role in the management of DRESS syndrome.
Dr. T. Simonart
Department of Dermatology, Erasme University Hospital
808, route de Lennik
B–1070 Brussels (Belgium)
Tel. +32 2 555 46 12, Fax +32 2 555 49 69, E-Mail firstname.lastname@example.org
Number of Print Pages : 4
Number of Figures : 0, Number of Tables : 1, Number of References : 30
Dermatology (International Journal for Clinical and Investigative Dermatology)
Founded as ‘Dermatologische Zeitschrift’ by Oskar Lassar (1893–1907); Continued by Erich Hoffmann (1908–1938), continued as ‘Dermatologica’ (1939–1991), by Wilhelm Lutz (1939–1958), Rudolf Schuppli (1959–1985)
Official Organ of the Swiss Society for Dermatology and Venereology; Official Organ of the Belgian Royal Society for Dermatology and Venereology
Vol. 206, No. 4, Year 2003 (Cover Date: 2003)
Journal Editor: J.-H. Saurat, Geneva.
ISSN: 1018–8665 (print), 1421–9832 (Online)
For additional information: http://www.karger.com/journals/drm