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Vol. 39, No. 1, 2003
Issue release date: July 2003
Section title: Original Paper
Pediatr Neurosurg 2003;39:44–49
(DOI:10.1159/000070880)

Epilepsy Surgery in Infancy

A Review of Four Cases

Olavarria G. · Petronio J.A.
aDepartment of Neurosurgery, Children’s Memorial Hospital, Chicago, Ill. and bSt. Paul Neurosurgical, St. Paul, Minn., USA

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Article / Publication Details

First-Page Preview
Abstract of Original Paper

Received: 4/2/2002
Accepted: 2/26/2003
Published online: 6/6/2003

Number of Print Pages: 6
Number of Figures: 9
Number of Tables: 0

ISSN: 1016-2291 (Print)
eISSN: 1423-0305 (Online)

For additional information: http://www.karger.com/PNE

Abstract

It has been demonstrated that intractable seizures in children can be eliminated or become more responsive to anticonvulsant medication after surgical resection of the epileptogenic focus or dysfunctional hemisphere. We describe our surgical experience with 4 infants treated at Children’s Healthcare of Atlanta Egleston Hospital between 1994 and 2002. All infants, ranging in age from 5 to 9 months, presented with severe seizure disorders and failed trials of anticonvulsants. All had preoperative EEG monitoring and MRI studies; 2 had PET functional imaging. One infant underwent a temporal resection for a low-grade glioma. The rest had cortical resections for malformations and dysplasia. All had improvement, with 2 infants free of seizures off medication. We argue for early intervention in severe cases, as the potential for recovery can be dramatic.


  

Author Contacts

Greg Olavarria, MD
Department of Neurosurgery
Children’s Memorial Hospital, 2300 Children’s Plaza, No. 28
Chicago, IL 60614 (USA)
Tel. +1 773 880 4373, Fax +1 773 880 4311, E-Mail golavarr@childrensmemorial.org

  

Article Information

Received: April 2, 2002
Accepted: February 26, 2003
Number of Print Pages : 6
Number of Figures : 9, Number of Tables : 0, Number of References : 25

  

Publication Details

Pediatric Neurosurgery
Founded 1985 by E.B. Hendrick and D.H. Reigel; Editor-in-Chief 1992–1996: F.J. Epstein, 1986–1998: D.H. Reigel, 1997–2002: D.G. McLone
Official Journal of the American Society of Pediatric Neurosurgeons (ASPN)

Vol. 39, No. 1, Year 2003 (Cover Date: July 2003)

Journal Editor: W.J. Oakes, Birmingham, Ala.; M.L. Walker, Salt Lake City, Utah
ISSN: 1016–2291 (print), 1423–0305 (Online)

For additional information: http://www.karger.com/pne


Article / Publication Details

First-Page Preview
Abstract of Original Paper

Received: 4/2/2002
Accepted: 2/26/2003
Published online: 6/6/2003

Number of Print Pages: 6
Number of Figures: 9
Number of Tables: 0

ISSN: 1016-2291 (Print)
eISSN: 1423-0305 (Online)

For additional information: http://www.karger.com/PNE


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Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in goverment regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
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