A Rare Inflammatory Pathology Mimicking Bladder NeoplasmsKiliç S. · Erguvan R. · Ipek D. · Gökçe H. · Güneş A. · Aydin N.E. · Baydinç C.
Departments of aUrology and bPathology, Inonu University Medical Faculty, Turgut Özal Medical Center, Malatya, Turkey
Purpose: We present a large series of eosinophilic cystitis including 8 cases; 3 of them had tumor-like lesions. Materials and Methods: The archives of pathology clinic of Inonu University Medical Faculty were reviewed from 1988 to 2002. The characteristics of patients and their diseases were recorded. Data obtained from 180 cases (172 from the literature and 8 from the present series) was assessed. Results: Seven cases had symptoms such as dysuria, frequency, hematuria, suprapubic pain, and difficulty in voiding. One asymptomatic case with history of bladder carcinoma was diagnosed during routine cystoscopy. The findings were microhematuria in 6 cases, macrohematuria in 2, pyuria in 3, urinary infection in 1, eosinophilia in 1, hyperazotemia in 1, and bladder masses in 3. Cystoscopies detected edematous and erythematous areas in 5 cases and lesions mimicking bladder carcinoma in 3. One case did not take further treatment after cystoscopy and biopsy and completely recovered. Four cases underwent medical therapy with nonsteroidal anti-inflammatory drugs and antihistaminics. They became asymptomatic and control cystoscopies showed no abnormal finding. Two of three patients with mass lesions recovered after steroid therapy following transurethral resection. The lesion in the third recurred and he improved after a second course of steroid therapy. Conclusions: Eosinophilic cystitis is a rare pathology. Sometimes, it may simulate bladder malignancies. Biopsy is mandatory at diagnosis. Usually, it has a benign course and may be treated with fulguration, analgesics, antihistaminics and steroids, although recurrence is possible.
Inönü Üniversitesi Tıp Fakültesi, Turgut Özal Tıp Merkezi, Üroloji
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Received: May 28, 2002
Accepted after revision: November 6, 2002
Number of Print Pages : 5
Number of Figures : 2, Number of Tables : 0, Number of References : 15
Founded 1955 by G. Peter A. Narath and Heinrich Heusser; Continued 1968–1987 by G. Mayor
Vol. 71, No. 3, Year 2003 (Cover Date: Released October 2003)
Journal Editor: D. Hauri, Zürich; M. Porena, Perugia; M.P. Wirth, Dresden
ISSN: 0042–1138 (print), 1423–0399 (Online)
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