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Vol. 56, No. 2, 2003
Issue release date: September 2003
Section title: Original Article
Gynecol Obstet Invest 2003;56:61–64
(DOI:10.1159/000072734)

Intravenous Nitroglycerin in the Management of Retained Placenta

Chedraui P.A.a,b · Insuasti D.F.a
aLabor Unit of the Enrique C. Sotomayor Obstetrics and Gynecology Hospital, and bInstitute of Biomedicine, Facultad de Ciencias Médicas, Universidad Católica de Santiago de Guayaquil, Guayaquil, Ecuador

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Article / Publication Details

First-Page Preview
Abstract of Original Article

Received: 4/23/2002
Accepted: 6/24/2003
Published online: 9/18/2003
Issue release date: September 2003

Number of Print Pages: 4
Number of Figures: 0
Number of Tables: 3

ISSN: 0378-7346 (Print)
eISSN: 1423-002X (Online)

For additional information: http://www.karger.com/GOI

Abstract

Thirty patients in the third stage of delivery complicated by retained placenta were prospectively managed with intravenous nitroglycerin. We studied the effect of nitroglycerin on the hemodynamics and characteristics of the procedure, and also analyzed labor and maternal and neonatal data. Intravenous nitroglycerin effectively aided the extraction of the retained placenta in all cases. The average procedure time was 5.3 ± 1.1 min, and the dose range was 50–200 µg. Systolic and diastolic blood pressure fell significantly from 111 ± 7.5 to 103 ± 6 mm Hg and from 74 ± 6.7 to 67 ± 6.6 mm Hg, respectively (p < 0.05). Although statistically significant, this was not evident clinically and there were no complications. Intravenous nitroglycerin at a dose of 200 µg or less is safe, effective and predictable in the management of retained placenta and could obviate the need of general anesthesia.

© 2003 S. Karger AG, Basel


  

Author Contacts

Peter Chedraui MD
Institute of Biomedicine, Facultad de Ciencias Médicas
Universidad Católica de Santiago de Guayaquil
PO Box 09-01-4671, Guayaquil (Ecuador)
Tel./Fax +593 4 220 6958, E-Mail peterchedraui@yahoo.com

  

Article Information

Received: April 23, 2002
Accepted after revision: June 24, 2003
Published online: August 4, 2003
Number of Print Pages : 4
Number of Figures : 0, Number of Tables : 3, Number of References : 34

  

Publication Details

Gynecologic and Obstetric Investigation
Founded 1895 as ‘Monatsschrift für Geburtshilfe und Gynäkologie’, continued 1946–1969 as ‘Gynaecologia’ and 1970 –1977 as ‘Gynecologic Investigation’

Vol. 56, No. 2, Year 2003 (Cover Date: Published online first (Issue-in-Progress))

Journal Editor: T.M. D'Hooghe, Leuven; J. Yankowitz, Iowa City, Iowa
ISSN: 0378–7346 (print), 1423–002X (Online)

For additional information: http://www.karger.com/journals/goi


Article / Publication Details

First-Page Preview
Abstract of Original Article

Received: 4/23/2002
Accepted: 6/24/2003
Published online: 9/18/2003
Issue release date: September 2003

Number of Print Pages: 4
Number of Figures: 0
Number of Tables: 3

ISSN: 0378-7346 (Print)
eISSN: 1423-002X (Online)

For additional information: http://www.karger.com/GOI


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Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in goverment regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
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