Risk Factors Associated with Childbearing-Related Episodes in Women with Bipolar DisorderAkdeniz F.a · Vahip S.a · Pirildar S.a · Vahip I.a · Doganer I.a · Bulut I.b
aEge University School of Medicine, Department of Psychiatry, Izmir and bBalat Hospital, Istanbul, Turkey
Objective: For the onset of illness and possible recurrence during the childbearing period, women with bipolar disorder (BD) are at a higher risk. The aim of this study was to evaluate the impact of clinical and psychosocial factors associated with pregnancy and the postpartum period on the course of BD. Methods: The childbearing and illness history of 72 women with BD were assessed to determine mood episodes related to the childbearing period. Data was analyzed to evaluate the risk factors (clinical, obstetric and psychosocial factors) related with mood episodes during pregnancy and the postpartum period. Results: Data of 252 pregnancies and childbirths of 72 women with BD were included in the analysis. Twenty-three (32%) women with BD reported at least one mood episode during pregnancy or within 1 month after childbirth (childbearing-related episode, CBRE). Subjects with CBREs mean age at onset of illness and mean age at the time of assessment were significantly younger than subjects with N-CBRE. A lower number of women who experienced a postpartum episode after the birth of the first child chose to have the second one. Psychosocial factors during pregnancy and the postpartum period and method of delivery did not predict the first postpartum episode. Onset of illness at an early age, experiencing episode during the first pregnancy and experiencing physical problems during pregnancy predicted a mood episode during the first postpartum period. Conclusions: Interpretation of the results of the study is limited with the retrospective nature of data collection. Within the limitations, we may suggest that psychosocial factors do not play a significant role in the genesis of CBREs in women with BD.
© 2003 S. Karger AG, Basel
Fisun Akdeniz, MD
Ege Universitesi Tip Fakultesi
Psikiyatri Anabilim Dali
TR–35100 Bornova/Izmir (Turkey)
Tel./Fax +90 232 3398804, E-Mail firstname.lastname@example.org
This study was presented at the Second European Stanley Foundation Bipolar Disorder Meeting, Amsterdam 2000 as a poster titled ‘Women with bipolar disorder: The effects of pregnancy and postpartum period on the course’.
Received: November 26, 2002
Accepted after revision: June 24, 2003
Number of Print Pages : 5
Number of Figures : 0, Number of Tables : 2, Number of References : 19
Psychopathology (International Journal of Descriptive and Experimental Psychopathology, Phenomenology and Psychiatric Diagnosis)
Founded 1897 as ‘Monatsschrift für Psychiatrie und Neurologie’
Official Journal of the World Psychiatric Association (WPA), Section of Clinical Psychopathology and Section of Classification and Diagnostic Assessment
Vol. 36, No. 5, Year 2003 (Cover Date: September-October 2003)
Journal Editor: C. Mundt, Heidelberg; E. Gabriel, Vienna; J.E. Mezzich, New York, N.Y.
ISSN: 0254–4962 (print), 1423–033X (Online)
For additional information: http://www.karger.com/psp