Hemorrhagic Complications of Microelectrode-Guided Deep Brain StimulationBinder D.K.a · Rau G.b · Starr P.A.a,b
aDepartment of Neurological Surgery, University of California, and bParkinson’s Disease Research Education and Clinical Center, SanFranciscoVA Medical Center, San Francisco, Calif., USA
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Background: The incidence of intracranial hemorrhage occurring during microelectrode-guided implantation of deep brain stimulators (DBS) for movement disorders has not been well defined. We report the incidence of hemorrhage in a large series of DBS implants into the subthalamic nucleus (STN), thalamus (VIM) and internal globus pallidus (GPi). Methods: All DBS procedures performed by a single surgeon (P.A.S.) between June 1998 and April 2003 were included in this study. Patients had postoperative imaging (MRI or CT) 4–24 h following surgery, and all hematomas >0.2 cm3 in volume were noted and scored as symptomatic (associated with any new neurologic deficit lasting >24 h) or asymptomatic. Results: The total number of lead implants was 357. There were 5 symptomatic hematomas and 6 asymptomatic hematomas. The relative risk of hematoma (any type) per lead implant was 3.1%. The incidence of hematoma by target site was 2.5% per lead for STN-DBS, 6.7% for GPi-DBS and 0% for VIM-DBS. Conclusion: The overall risk of intraoperative or early postoperative symptomatic hemorrhage with microelectrode-guided DBS, over all targets, was 1.4% per lead implant. The brain target had a significant effect on the risk of hemorrhage.
© 2003 S. Karger AG, Basel
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