The Zebrafish as a Model Organism for Eye DevelopmentGlass A.S. · Dahm R.
aMedizinische Genetik, Eberhard-Karls-Universität Tübingen, and bMax Planck Institute for Developmental Biology, Tübingen, Germany
In recent years, the zebrafish has become a favourite model organism for biologists studying developmental processes in vertebrates. Its rapid embryonic development, the transparency of its embryos, the large number of offspring together with several other advantages make it ideal for discovering and understanding the genes that regulate embryonic development as well as the physiology of the adult organism. Zebrafish are very visually orientated, and their retina and lens show much the same morphology as other vertebrates including humans. For this reason, they are well suited for examining ocular development, function and disease. This review describes the advantages of the zebrafish as a model organism as well as giving an overview of eye development in this species. It has a particular focus on morphological as well as molecular aspects of the development of the lens.
Max Planck Institute for Developmental Biology
DE–72076 Tübingen (Germany)
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Received: November 22, 2003
Accepted: December 9, 2003
Number of Print Pages : 21
Number of Figures : 6, Number of Tables : 0, Number of References : 176
Ophthalmic Research (Journal for Research in Experimental and Clinical Ophthalmology)
Founded 1970 by O. Hockwin, Bonn, G. Naumann, Hamburg and D.F. Cole, London
Vol. 36, No. 1, Year 2004 (Cover Date: January-February 2004)
Journal Editor: Gijs F.J.M. Vrensen, Zeist
ISSN: 0030–3747 (print), 1423–0259 (Online)
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