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Table of Contents
Vol. 1, No. 1, 2004
Issue release date: April 2004
Section title: Mini Review
Neurodegenerative Dis 2004;1:9–19

Neuronal Apoptosis in Neurodegenerative Diseases: From Basic Research to Clinical Application

Kermer P. · Liman J. · Weishaupt J.H. · Bähr M.
Department of Neurology, University of Göttingen, Göttingen, Germany
email Corresponding Author

Dr. Pawel Kermer

Department of Neurology, University of Göttingen

Robert-Koch-Strasse 40

DE–37075 Göttingen (Germany)

Tel. +49 551 394 927, Fax +49 551 391 4302, E-Mail pkermer@gwdg.de

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In recent years, the investigation of erroneous regulation of apoptotic mechanisms during acute and chronic injury of neuronal cells has gained increasing attention. Besides acute neuronal trauma and ischemia, chronic neurodegenerative diseases like Alzheimer’s, Huntington’s, Parkinson’s and Lou-Gehrig’s disease (amyotrophic lateral sclerosis) are of particular interest. The present article will provide an overview of basic apoptotic mechanisms, the contribution of neuronal apoptosis to the above-mentioned disorders, potential clinical applications and their limitations and the possible implications for future studies regarding these neurodegenerative diseases.

© 2004 S. Karger AG, Basel

Article / Publication Details

First-Page Preview
Abstract of Mini Review

Published online: April 29, 2004
Issue release date: April 2004

Number of Print Pages: 11
Number of Figures: 2
Number of Tables: 1

ISSN: 1660-2854 (Print)
eISSN: 1660-2862 (Online)

For additional information: http://www.karger.com/NDD

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