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Vol. 73, No. 5, 2004
Issue release date: September–October 2004
Section title: Clinical Note
Psychother Psychosom 2004;73:324–328
(DOI:10.1159/000078850)

QT Interval and QT Dispersion in Eating Disorders

Takimoto Y. · Yoshiuchi K. · Kumano H. · Yamanaka G. · Sasaki T. · Suematsu H. · Nagakawa Y. · Kuboki T.
aDepartment of Psychosomatic Medicine, Faculty of Medicine, The University of Tokyo, Tokyo, bKawamuragakuen Women’s College, Chiba, and cHealth Care Center, Ochanomizu University, Tokyo, Japan

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Article / Publication Details

First-Page Preview
Abstract of Clinical Note

Published online: 7/30/2004

Number of Print Pages: 5
Number of Figures: 0
Number of Tables: 3

ISSN: 0033-3190 (Print)
eISSN: 1423-0348 (Online)

For additional information: http://www.karger.com/PPS

Abstract

Background: Eating disorders are thought to be risk factors for cardiac sudden death secondary to arrhythmia. Results in previous studies on QT interval and QT dispersion, markers of fatal arrhythmia, have been inconsistent. Methods: We prospectively examined 179 female eating disorder patients, being over 18 years old and diagnosed according to the DSM-IV criteria between January 1995 and December 2002, and 52 healthy women. Patients with abnormal plasma electrolytes or taking medications that might influence the electrocardiogram (ECG) were excluded from the study. QT intervals were corrected for heart rate using Bazett’s formula and the nomogram method, which is more reliable at extremely low heart rates than Bazett’s formula. QT dispersion was measured as the difference between the longest and shortest QT intervals. QT intervals and QT dispersion in each patient group were compared with those in the control group. Results: The 164 eligible patients consisted of 43 patients with anorexia nervosa restricting type, 35 with anorexia nervosa binge eating/purging type, 63 with bulimia nervosa purging type, and 23 with bulimia nervosa nonpurging type. There was no significant difference in age between eating disorder patients and controls. QT interval and QT dispersion were significantly longer in all eating disorder subtypes than in the control group. QT interval and QT dispersion were significantly correlated with the rate of body weight loss in bulimia nervosa. Conclusions: QT interval and QT dispersion were prolonged in both anorexia nervosa and bulimia nervosa. Examination of ECG in eating disorder patients without extremely low body weight also appears to be clinically important.


  

Author Contacts

Yoshiyuki Takimoto
Department of Psychosomatic Medicine
Faculty of Medicine, The University of Tokyo
Hongo 7-3-1, Bunkyo-ku, Tokyo 113-8655 (Japan)
Tel./Fax +81 5800 9737, E-Mail taki-tky@umin.ac.jp

  

Article Information

Number of Print Pages : 5
Number of Figures : 0, Number of Tables : 3, Number of References : 21

  

Publication Details

Psychotherapy and Psychosomatics
Founded 1953 as ‘Acta Psychotherapeutica et Psychosomatica’ by E.A.D.E. Carp and B. Stokvis, continued by Th. Spoerri (1964–1974) and P.E. Sifneos (1974–1991)
Official Journal of the International College of Psychosomatic Medicine (ICPM)

Vol. 73, No. 5, Year 2004 (Cover Date: September-October 2004)

Journal Editor: G.A. Fava, Bologna
ISSN: 0033–3190 (print), 1423–0348 (Online)

For additional information: http://www.karger.com/journals/pps


Article / Publication Details

First-Page Preview
Abstract of Clinical Note

Published online: 7/30/2004

Number of Print Pages: 5
Number of Figures: 0
Number of Tables: 3

ISSN: 0033-3190 (Print)
eISSN: 1423-0348 (Online)

For additional information: http://www.karger.com/PPS


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