The purpose of this study was to evaluate whether bacterial biofilms exist on the sinus mucosa surfaces of human subjects with recalcitrant chronic sinusitis. Scanning electron microscopy was used to evaluate patients with continued symptoms of chronic sinusitis despite prior appropriate medical and surgical management. Morphologic structures that confirm the presence of bacterial biofilms were identified on the sinus mucosa of patients infected with Pseudomonas aeruginosa, a known biofilm former. The presence of bacterial biofilms may explain the recalcitrant nature of some forms of chronic sinusitis.
© 2004 S. Karger AG, Basel
James N. Palmer, MD
Division of Rhinology, Department of Otorhinolaryngology – Head and Neck Surgery
University of Pennsylvania Medical Center –5 Ravdin
3400 Spruce Street, Philadelphia, PA 19104 (USA)
Tel. +1 215 662 7746, Fax +1 215 614 0071
Received: June 9, 2004
Accepted: June 16, 2004
Number of Print Pages : 4
Number of Figures : 2, Number of Tables : 0, Number of References : 6
ORL (Journal for Oto-Rhino-Laryngology and Its Related Specialties)
Founded 1938 as ‘Practica Oto-Rhino-Laryngologica’ by J. Berberich and E. Schlittler, continued by L. Rüedi 1947–1970, E. Huizinga 1948–1970, C.R. Pfaltz 1968–1984
Vol. 66, No. 3, Year 2004 (Cover Date: 2004)
Journal Editor: B.W. O’Malley, Baltimore, Md.
ISSN: 0301–1569 (print), 1423–0275 (Online)
For additional information: http://www.karger.com/orl
Article / Publication Details
Published online: 8/19/2004
Issue release date: 2004
Number of Print Pages: 4
Number of Figures: 2
Number of Tables: 0
ISSN: 0301-1569 (Print)
eISSN: 1423-0275 (Online)
For additional information: http://www.karger.com/ORL
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