Background: In a case monitored by the Norwegian National Register for Severe Allergic Reactions to Food, a patient with peanut allergy experienced an allergic reaction after eating a particular brand of hot dog bread. The aim of this study was to identify the eliciting allergen. Methods: Extracts from the hot dog bread and reference material from peanut, lupine and lupine-fortified food products were analysed by immunochemical methods with patient serum and a new polyclonal anti-lupine antibody. Results: Evidence could be provided that the hot dog bread contained proteins from lupine but not from peanut. Conclusion: Crossed peanut-lupine allergy can have clinical significance. A peanut-allergic patient reacted against hidden lupine protein in a hot dog bread. Presented with our results, the producer confirmed the use of lupine flour and changed the ingredient list.
© 2004 S. Karger AG, Basel
Correspondence to: Dr. Christiane K. Fæste
National Veterinary Institute
PO Box 8156, dep.
NO–0033 Oslo (Norway)
Tel. +47 23216232, Fax +47 23216201, E-Mail firstname.lastname@example.org
Received: July 8, 2003
Accepted after revision: May 17, 2004
Published online: July 29, 2004
Number of Print Pages : 4
Number of Figures : 2, Number of Tables : 0, Number of References : 19
International Archives of Allergy and Immunology
Official Journal of the Collegium Internationale Allergologicum
Vol. 135, No. 1, Year 2004 (Cover Date: September 2004)
Journal Editor: R. Valenta, Vienna
ISSN: 1018–2438 (print), 1423–0097 (Online)
For additional information:http://www.karger.com/iaa
Article / Publication Details
Published online: 9/22/2004
Issue release date: September 2004
Number of Print Pages: 4
Number of Figures: 2
Number of Tables: 0
ISSN: 1018-2438 (Print)
eISSN: 1423-0097 (Online)
For additional information: http://www.karger.com/IAA
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