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Table of Contents
Vol. 107, No. 3-4, 2004
Issue release date: October 2004
Section title: Paper
Cytogenet Genome Res 107:201–207 (2004)
(DOI:10.1159/000080598)

Roles of RecA homologues Rad51 and Dmc1 during meiotic recombination

Shinohara A.a,b,c · Shinohara M.a
aInstitute for Protein Research and bGraduate School of Science, Osaka University, Osaka; cPRESTO, Japan Science Technology Agency, Saitama (Japan)

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Article / Publication Details

First-Page Preview
Abstract of Paper

Received: January 06, 2004
Accepted: March 18, 2004
Published online: October 14, 2004
Issue release date: October 2004

Number of Print Pages: 7
Number of Figures: 2
Number of Tables: 0

ISSN: 1424-8581 (Print)
eISSN: 1424-859X (Online)

For additional information: http://www.karger.com/CGR

Abstract

RecA protein is involved in homology search and strand exchange processes during recombination. Mitotic cells in eukaryotes express one RecA, Rad51, which is essential for the repair of double-strand breaks (DSBs). Additionally, meiotic cells induce the second RecA, Dmc1. Both Rad51 and Dmc1 are necessary to generate a crossover between homologous chromosomes, which ensures the segregation of the chromosomes at meiotic division I. It is largely unknown how the two RecAs cooperate during meiotic recombination. In this review, recent advances on our knowledge about the roles of Rad51 and Dmc1 during meiosis are summarized and discussed.   

© 2004 S. Karger AG, Basel


Article / Publication Details

First-Page Preview
Abstract of Paper

Received: January 06, 2004
Accepted: March 18, 2004
Published online: October 14, 2004
Issue release date: October 2004

Number of Print Pages: 7
Number of Figures: 2
Number of Tables: 0

ISSN: 1424-8581 (Print)
eISSN: 1424-859X (Online)

For additional information: http://www.karger.com/CGR


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