Gastrinomas causing Zollinger-Ellison syndrome (ZES) are the most common functional, malignant pancreatic endocrine tumors. In this paper, the diagnosis and treatment of these tumors are reviewed, incorporating recent advances in each area. Furthermore, recent advances in their pathology, molecular pathogenesis, and aspects of their localization using somatostatin receptor scintigraphy, as well as their treatment are discussed. Recent data from our NIH prospective studies on patients with ZES are included to illustrate many of these points.
Robert T. Jensen
NIH/NIDDK/DDB, Bldg. 10, Rm. 9C-103
10 Center DR MSC 1804
Bethesda MD 20892-1804 (USA)
Tel. +1 301 496 4201, Fax +1 301 402 0600, E-Mail firstname.lastname@example.org
Number of Print Pages : 5
Number of Figures : 2, Number of Tables : 2, Number of References : 18
Neuroendocrinology (International Journal for Basic and Clinical Studies on Neuroendocrine Relationships)
Vol. 80, No. Suppl. 1, Year 2004 (Cover Date: Released October 2004)
Journal Editor: C. Kordon, Paris
ISSN: 0028–3835 (print), 1423–0194 (Online)
For additional information: http://www.karger.com/nen
Article / Publication Details
Published online: 10/15/2004
Issue release date: October 2004
Number of Print Pages: 5
Number of Figures: 2
Number of Tables: 2
ISSN: 0028-3835 (Print)
eISSN: 1423-0194 (Online)
For additional information: http://www.karger.com/NEN
Copyright / Drug Dosage
Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher or, in the case of photocopying, direct payment of a specified fee to the Copyright Clearance Center.
Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in goverment regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.