Gastrinomas causing Zollinger-Ellison syndrome (ZES) are the most common functional, malignant pancreatic endocrine tumors. In this paper, the diagnosis and treatment of these tumors are reviewed, incorporating recent advances in each area. Furthermore, recent advances in their pathology, molecular pathogenesis, and aspects of their localization using somatostatin receptor scintigraphy, as well as their treatment are discussed. Recent data from our NIH prospective studies on patients with ZES are included to illustrate many of these points.
Robert T. Jensen
NIH/NIDDK/DDB, Bldg. 10, Rm. 9C-103
10 Center DR MSC 1804
Bethesda MD 20892-1804 (USA)
Tel. +1 301 496 4201, Fax +1 301 402 0600, E-Mail email@example.com
Number of Print Pages : 5
Number of Figures : 2, Number of Tables : 2, Number of References : 18
Neuroendocrinology (International Journal for Basic and Clinical Studies on Neuroendocrine Relationships)
Vol. 80, No. Suppl. 1, Year 2004 (Cover Date: Released October 2004)
Journal Editor: C. Kordon, Paris
ISSN: 0028–3835 (print), 1423–0194 (Online)
For additional information: http://www.karger.com/nen
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