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Table of Contents
Vol. 71, No. 6, 2004
Issue release date: November–December 2004
Section title: Clinical Investigations
Respiration 2004;71:559–566
(DOI:10.1159/000081755)

Outpatient Management of Malignant Pleural Effusions with Small-Bore, Tunneled Pleural Catheters

Musani A.I. · Haas A.R. · Seijo L. · Wilby M. · Sterman D.H.
Interventional Pulmonology Program, Division of Pulmonary, Allergy and Critical Care Medicine, University of Pennsylvania Medical Center, Philadelphia, Pa., USA

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Article / Publication Details

First-Page Preview
Abstract of Clinical Investigations

Received: 8/18/2003
Accepted: 4/15/2004
Published online: 12/13/2004

Number of Print Pages: 8
Number of Figures: 4
Number of Tables: 1

ISSN: 0025-7931 (Print)
eISSN: 1423-0356 (Online)

For additional information: http://www.karger.com/RES

Abstract

Background: Malignant pleural effusions (MPEs) can produce significant respiratory symptoms and diminished quality of life in patients with terminal malignancies. Control of MPEs to palliate respiratory symptoms can be performed via several different approaches. Ideally, a minimally invasive procedure to control MPEs and to provide relief of respiratory symptoms would be optimal. Objective: To ascertain if control of MPEs can be achieved by outpatient management via a small-bore pleural catheter (PC) without the need for sclerosing agents. Methods: Retrospective chart analysis of 24 patients after outpatient insertion of PCs for recurrent, symptomatic MPEs followed by frequent home drainage of pleural fluid to relieve respiratory symptoms. Results: Symptomatic relief of respiratory symptoms was achieved in 100% of patients, while pleurodesis was achieved in 58% of patients in a mean of 39 days. Five patients (6 PCs) expired with the catheters in place. In these patients, all catheters remained in position and functional until the patients ultimately died from nonpleural disease progression. No major complications occurred during insertion of the catheter. Late complications included localized cellulitis and bacterial superinfection in three patients and tumor growth at the catheter site in one patient. Conclusions: The PCs used in the present study provided an effective modality not only to alleviate respiratory symptoms associated with MPE, but also to achieve pleurodesis in 58% of our patients. These catheters may provide a significantly less invasive outpatient approach to the palliative management of MPEs.


  

Author Contacts

Ali I. Musani, MD, Associate Director
Interventional Pulmonology Program, Pulmonary, Allergy and Critical Care Division
3600 Spruce Street, Hospital of the University of Pennsylvania
Philadelphia, PA 19104-4283 (USA)
Tel. +1 215 615 0786, Fax +1 215 614 0518, E-Mail amusani@mail.med.upenn.edu

  

Article Information

A.I.M. and A.R.H. contributed equally to the production of this paper.

Received: August 18, 2003
Accepted after revision: April 15, 2004
Number of Print Pages : 8
Number of Figures : 4, Number of Tables : 1, Number of References : 28

  

Publication Details

Respiration (International Journal of Thoracic Medicine)

Vol. 71, No. 6, Year 2004 (Cover Date: November-December 2004)

Journal Editor: C.T. Bolliger, Cape Town
ISSN: 0025–7931 (print), 1423–0356 (Online)

For additional information: http://www.karger.com/res


Article / Publication Details

First-Page Preview
Abstract of Clinical Investigations

Received: 8/18/2003
Accepted: 4/15/2004
Published online: 12/13/2004

Number of Print Pages: 8
Number of Figures: 4
Number of Tables: 1

ISSN: 0025-7931 (Print)
eISSN: 1423-0356 (Online)

For additional information: http://www.karger.com/RES


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