Journal Mobile Options
Table of Contents
Vol. 59, No. 2, 2005
Issue release date: February 2005
Section title: Original Article
Gynecol Obstet Invest 2005;59:62–66
(DOI:10.1159/000081895)

Endocrine and Cognitive Effects of Short-Time Soybean Consumption in Women

Celec P. · Ostatníková D. · Cagánová M. · Žuchová S. · Hodosy J. · Putz Z. · Bernadič M. · Kúdela M.
Institutes of aPathophysiology and bPhysiology, Faculty of Medicine, Departments of cMolecular Biology, dGenetics, eAnimal Physiology and Ethology, and fZoology, Faculty of Natural Sciences, Comenius University, Bratislava, gNational Institute of Endocrinology and Diabetology, L’ubochňa, Slovakia

Do you have an account?

Register and profit from personalized services (MyKarger) Login Information

Please create your User ID & Password





Contact Information









I have read the Karger Terms and Conditions and agree.

Register and profit from personalized services (MyKarger) Login Information

Please create your User ID & Password





Contact Information









I have read the Karger Terms and Conditions and agree.

To view the fulltext, please log in

To view the pdf, please log in

Buy

  • FullText & PDF
  • Unlimited re-access via MyKarger (new!)
  • Unrestricted printing, no saving restrictions for personal use
  • Reduced rates with a PPV account
read more

Direct: USD 38.00
Account: USD 26.50

Select

Rent/Cloud

  • Rent for 48h to view
  • Buy Cloud Access for unlimited viewing via different devices
  • Synchronizing in the ReadCube Cloud
  • Printing and saving restrictions apply

Rental: USD 8.50
Cloud: USD 20.00

Select

Subscribe

  • Automatic perpetual access to all articles of the subscribed year(s)
  • Unlimited re-access via Subscriber Login or MyKarger
  • Unrestricted printing, no saving restrictions for personal use
read more

Subcription rates


Select


Article / Publication Details

First-Page Preview
Abstract of Original Article

Received: 5/3/2004
Accepted: 8/19/2004
Published online: 2/11/2005

Number of Print Pages: 5
Number of Figures: 3
Number of Tables: 0

ISSN: 0378-7346 (Print)
eISSN: 1423-002X (Online)

For additional information: http://www.karger.com/GOI

Abstract

Background: Soy phytoestrogens are known to influence the hormonal status acting as partial estrogen agonists. Soy-derived food supplements are advised for hormone replacement therapy, prevention of atherosclerosis, age-related cognitive decline and even hormone-dependent cancer, although results from clinical studies are controversial. Whether increased soybean intake can affect the endocrine status and cognitive abilities is largely unknown. Aim: To observe the effects of 1 week of increased soybean intake on sex hormone levels and spatial cognitive abilities in women. Subjects and Methods: 16 young healthy female volunteers were asked to eat 900 g of soybeans within 1 week. Salivary testosterone (T), free and total plasma T, salivary and plasma estradiol (E) were measured by radioimmunoassay before and after the study period. Mental rotation (MR) and spatial visualization (SV) psychological tests were done at the days of sampling. Results: Soybean intake increased total plasma T levels (p < 0.02) while decreasing salivary T (p < 0.01) and not altering free plasma T levels. Salivary and plasma E levels were not changed. The results of MR and SV tests were improved after the study period. Conclusion: Short-time increased soybean intake alters the level of total plasma and salivary T and improves spatial cognition in women. Whether this effect is mediated by modulation of estrogen receptors, changes in sex hormone-binding globulin production or changes in activity of steroid-competent enzymes needs further study.


  

Author Contacts

Peter Celec
Galbavého 3
SK–841 01 Bratislava (Slovakia)
Tel. +421 903 507 822, Fax +421 2 642 85 819
E-Mail petercelec@hotmail.com

  

Article Information

Received: May 3, 2004
Accepted after revision: August 19, 2004
Published online: November 3, 2004
Number of Print Pages : 5
Number of Figures : 3, Number of Tables : 0, Number of References : 36

  

Publication Details

Gynecologic and Obstetric Investigation

Vol. 59, No. 2, Year 2005 (Cover Date: Released February 2005)

Journal Editor: D'Hooghe, T. (Leuven)
ISSN: 0378–7346 (print), 1423–002X (Online)

For additional information: http://www.karger.com/goi


Article / Publication Details

First-Page Preview
Abstract of Original Article

Received: 5/3/2004
Accepted: 8/19/2004
Published online: 2/11/2005

Number of Print Pages: 5
Number of Figures: 3
Number of Tables: 0

ISSN: 0378-7346 (Print)
eISSN: 1423-002X (Online)

For additional information: http://www.karger.com/GOI


Copyright / Drug Dosage

Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher or, in the case of photocopying, direct payment of a specified fee to the Copyright Clearance Center.
Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in goverment regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.