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Vol. 19, No. 2-3, 2005
Issue release date: February 2005
Section title: Original Research Article
Dement Geriatr Cogn Disord 2005;19:67–74
(DOI:10.1159/000082351)

Prevalence of Mild Cognitive Impairment in 60- to 64-Year-Old Community-Dwelling Individuals: The Personality and Total Health through Life 60+ Study

Kumar R.a,b · Dear K.B.G.b · Christensen H.b · Ilschner S.b · Jorm A.F.b · Meslin C.b · Rosenman S.J.b · Sachdev P.S.c
aDepartment of Psychological Medicine, The Canberra Hospital, bCentre for Mental Health Research, Australian National University, Canberra, and cUniversity of New South Wales, Sydney, Australia

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Article / Publication Details

First-Page Preview
Abstract of Original Research Article

Received: 5/9/2004
Published online: 2/11/2005
Issue release date: February 2005

Number of Print Pages: 8
Number of Figures: 3
Number of Tables: 3

ISSN: 1420-8008 (Print)
eISSN: 1421-9824 (Online)

For additional information: http://www.karger.com/DEM

Abstract

This epidemiological study aimed at determining the prevalence of mild cognitive impairment (MCI) in 60- to 64-year-old individuals using different diagnostic criteria. Community dwelling individuals (n = 2,551) in the age range of 60–64 years were recruited randomly through the electoral roll. They were screened using the MMSE and a short cognitive battery, and those who screened positive underwent detailed medical and cognitive assessments. Extant MCI-related diagnoses were established by consensus. Predictive regression models on the sub-sample were used to determine population prevalence for the diagnoses. Of the 224 subjects who screened positive for MCI, 112 underwent a detailed assessment and 74% met the criteria for at least one recognised diagnosis of mild cognitive deficit (MCI and related diagnoses). By predictive regression modelling, the prevalence of any MCI diagnosis was 13.7% (95% CI 9.1–30.2) in the population of 60- to 64-year-olds. The estimated prevalence rates for specific diagnoses were: MCI 3.7%, ageing-associated cognitive decline 3.1%, Clinical Dementia Rating score (0.5) 2.8%, age-associated memory impairment 1%, other cognitive disorders 0.9%, and mild neurocognitive disorder 0.6%. Agreement on ‘caseness’ between various proposed diagnoses was at best fair and generally poor. Memory and other cognitive problems not meeting the threshold for dementia are relatively common in 60- to 64-year-old individuals living in the community. The prevalence rate varies up to six-fold according to the diagnostic criteria applied, with limited overlap between diagnoses. There is an urgent need for standardization of the criteria.

© 2005 S. Karger AG, Basel


Article / Publication Details

First-Page Preview
Abstract of Original Research Article

Received: 5/9/2004
Published online: 2/11/2005
Issue release date: February 2005

Number of Print Pages: 8
Number of Figures: 3
Number of Tables: 3

ISSN: 1420-8008 (Print)
eISSN: 1421-9824 (Online)

For additional information: http://www.karger.com/DEM


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