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Table of Contents
Vol. 19, No. 3, 2005
Issue release date: February 2005
Section title: Original Paper
Cerebrovasc Dis 2005;19:179–185
(DOI:10.1159/000083253)

Trends in Five-Year Survival and Risk of Recurrent Stroke after First-Ever Stroke in the Perth Community Stroke Study

Hardie K.a · Jamrozik K.b · Hankey G.J.c, d · Broadhurst R.J.a · Anderson C.e
aSchool of Population Health, University of Western Australia, Perth, Australia; bImperial College of Science, Technology and Medicine, London, UK; cStroke Unit, Department of Neurology, Royal Perth Hospital, and dSchool of Medicine and Pharmacology, University of Western Australia, Perth, Australia; eClinical Trials Research Unit, University of Auckland, New Zealand

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Article / Publication Details

First-Page Preview
Abstract of Original Paper

Received: May 07, 2004
Accepted: September 07, 2004
Published online: March 02, 2005
Issue release date: February 2005

Number of Print Pages: 7
Number of Figures: 1
Number of Tables: 5

ISSN: 1015-9770 (Print)
eISSN: 1421-9786 (Online)

For additional information: http://www.karger.com/CED

Abstract

Background: Few studies provide information on trends in the long-term outcome of stroke. Weaimed to determine trends in survival and recurrent stroke, over 5 years after first-ever stroke, for 2 cohorts of patients enrolled in the Perth Community Stroke Study in 1989–90 and 1995–96. Methods: For 12-month periods beginning February 1989 and February 1995, all individuals with an acute stroke who were resident in a geographically-defined and representative region of Perth, Western Australia, were registered and followed-up prospectively 5 years after the index event. Results: The 5-year cumulative risk of death was 59% (95% confidence interval (CI) 53%, 65%) and 58% (95% CI 52%, 65%) for the 1989–90 and 1995–96 cohorts, respectively (p = 0.94). The 5-year cumulative risk of first recurrent stroke was 32% (95% CI 25%, 40%) and 23% (95% CI 16%, 30%) for the 1989–90 and 1995–96 cohorts, respectively (p = 0.07). Conclusions: Although no statistically significant improvement occurred in 5-year survival after first-ever stroke in Perth between 1989–90 and 1995–96, there was a statistically nonsignificant trend towards a smaller cumulative risk of recurrent stroke over 5 years after a first-ever stroke. Serial community-based studies of the incidence and outcome of stroke are an important means of monitoring the translation of proven preventive interventions to improvements in population health.

© 2005 S. Karger AG, Basel


Article / Publication Details

First-Page Preview
Abstract of Original Paper

Received: May 07, 2004
Accepted: September 07, 2004
Published online: March 02, 2005
Issue release date: February 2005

Number of Print Pages: 7
Number of Figures: 1
Number of Tables: 5

ISSN: 1015-9770 (Print)
eISSN: 1421-9786 (Online)

For additional information: http://www.karger.com/CED


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