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Table of Contents
Vol. 28, No. 4, 2005
Issue release date: April 2005
Section title: Original Article · Originalarbeit
Onkologie 2005;28:187-192
(DOI:10.1159/000084061)

Outbreak of Vancomycin-Resistant Enterococci (VRE) in a Hematological Oncology Ward and Hygienic Preventive Measures. A Long-Term Study

Knoll M.a · Daeschlein G.b · Okpara-Hofmann J.a · Klare I.c · Wilhelms D.d · Wolf H.e · Borneff-Lipp M.a
aInstitut für Hygiene, Martin-Luther-Universität Halle-Wittenberg, bInstitut für Hygiene, Ernst-Arndt-Universität Greifswald, cRobert Koch-Institute Berlin, Bereich Wernigerode, dInstitut für Medizinische Mikrobiologie, Martin-Luther-Universität Halle-Wittenberg, eUniversitätsklinik und Poliklinik für Innere Medizin IV, Hämatologie und Onkologie, Martin-Luther-Universität Halle-Wittenberg, Germany

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Article / Publication Details

First-Page Preview
Abstract of Original Article · Originalarbeit

Published online: October 03, 2005
Issue release date: April 2005

Number of Print Pages: 6
Number of Figures: 0
Number of Tables: 0

ISSN: 2296-5270 (Print)
eISSN: 2296-5262 (Online)

For additional information: http://www.karger.com/ORT

Abstract

Background: We report on two endemic outbreaks of VRE (vancomycin-resistant enterococci, vanA type Ente-rococcus faecium) on a hematological oncology ward in a university hospital and a new strategic concept to fight against spread of VRE. Patients and Methods: During management of the outbreak, a total of 1,124 patients and 1,700 specimens were investigated from June 1999 to December 2001. Protective measures were instituted. Intensive prophylactic infection control was practiced until December 2003. Results: Of the 1,124 patients, 44 were VRE-positive. From 1,700 environment speci-mens, 110 VRE isolates were obtained from the inani-mate environment, 5 from the living environment. Mole-cular biological typing identified 5 different clones which had spread on the ward in different locations. Conclu-sion: The study shows the need for prophylactic microbi-ological screening investigations in the risk group of hematological oncology patients and consistent imple-mentation of protective hygiene measures to prevent the spread of multiresistant infectious pathogens on risk wards. It is also shown that intervention can to control such an endemic outbreak.


Article / Publication Details

First-Page Preview
Abstract of Original Article · Originalarbeit

Published online: October 03, 2005
Issue release date: April 2005

Number of Print Pages: 6
Number of Figures: 0
Number of Tables: 0

ISSN: 2296-5270 (Print)
eISSN: 2296-5262 (Online)

For additional information: http://www.karger.com/ORT


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Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
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