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Table of Contents
Vol. 14, No. 4, 2005
Issue release date: July – August
Section title: Case Report

Open Access Gateway

Med Princ Pract 2005;14:281–283

Late Development of Diabetes mellitus after Interferon-Alfa and Ribavirin Therapy for Chronic Hepatitis C: A Case Report

Radhakrishnan S.a · Upadhyay A.a · Mohan N.a · Dhar A.a · Walia H.a · Zubaidi G.b
Departments of aGastroenterology and bEndocrinology, The Royal Hospital, Muscat, Oman
email Corresponding Author

Dr. S. Radhakrishnan, FRCP (Edin)

Gastroenterology Division

The Royal Hospital, PO Box 1331, CPO 111

Muscat (Oman)

Tel./Fax +968 594461, E-Mail jagan01@omantel.net.om

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Objective: To report the late development of immune-mediated diabetes mellitus after completion of alfa-interferon therapy for hepatitis C in an Asian patient. Clinical Presentation and Intervention: A 50-year-old male with chronic hepatitis C received treatment with alfa-interferon and ribavirin for 52 weeks. He developed immune-mediated diabetes mellitus with low C-peptide and positive antiglutamic acid decarboxylase antibody after completion of therapy. The hepatitis C infection was eradicated, but he continued to be diabetic requiring insulin therapy during the follow-up. Conclusion: This report shows thatimmune-mediateddiabetes mellitus can occur as a late complication of alfa-interferon therapy.

© 2005 S. Karger AG, Basel

Article / Publication Details

First-Page Preview
Abstract of Case Report

Received: October 21, 2003
Accepted: June 02, 2004
Published online: June 13, 2005
Issue release date: July – August

Number of Print Pages: 3
Number of Figures: 0
Number of Tables: 0

ISSN: 1011-7571 (Print)
eISSN: 1423-0151 (Online)

For additional information: http://www.karger.com/MPP

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