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Vol. 54, No. 1, 2005
Issue release date: September 2005
Section title: Original Paper
Eur Neurol 2005;54:10–13
(DOI:10.1159/000086755)

Prognosis following Postanoxic Myoclonus Status epilepticus

Hui A.C.F. · Cheng C. · Lam A. · Mok V. · Joynt G.M.
Departments of aMedicine and Therapeutics, and bAnesthesia and Intensive Care, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, and cDepartment of Medicine, Caritas Medical Center, Shamshuipo, Kowloon, Hong Kong, SAR, China

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Article / Publication Details

First-Page Preview
Abstract of Original Paper

Received: 12/2/2004
Accepted: 5/6/2005
Published online: 9/9/2005

Number of Print Pages: 4
Number of Figures: 0
Number of Tables: 2

ISSN: 0014-3022 (Print)
eISSN: 1421-9913 (Online)

For additional information: http://www.karger.com/ENE

Abstract

Prediction of outcome after cardiac arrest has important ethical and socioeconomic implications. In general, delay in recovery of neurological function is associated with a worse prognosis. The presence of myoclonic seizures early after anoxia has been identified as a poor prognostic factor. We report a series of patients who developed postanoxic myoclonus status epilepticus (MSE), which was defined as continuous myoclonic seizure activity lasting 30 min or more. The results from 18 patients were retrieved, 11 men and 7 women, age ranging from 29 to 90 years. Myoclonus developed a mean of 11.7 h after cardiac arrest, persisting for a mean of 60.5 h. Sixteen (89%) died following MSE and the 2 survivors were highly dependent or remained in a persistent vegetative state, supporting the view that prognosis is poor in this condition.


  

Author Contacts

Andrew C.F. Hui, FRCP
Department of Medicine and Therapeutics, Prince of Wales Hospital
The Chinese University of Hong Kong
Shatin, Hong Kong, SAR (China)
Tel. +852 26323131, +852 26323133, Fax +852 26375396, E-Mail cfhui@cuhk.edu.hk

  

Article Information

Received: December 2, 2004
Accepted: May 6, 2005
Published online: July 5, 2005
Number of Print Pages : 4
Number of Figures : 0, Number of Tables : 2, Number of References : 26

  

Publication Details

European Neurology

Vol. 54, No. 1, Year 2005 (Cover Date: Released September 2005)

Journal Editor: Bogousslavsky, J. (Lausanne)
ISSN: 0014–3022 (print), 1421–9913 (Online)

For additional information: http://www.karger.com/ene


Article / Publication Details

First-Page Preview
Abstract of Original Paper

Received: 12/2/2004
Accepted: 5/6/2005
Published online: 9/9/2005

Number of Print Pages: 4
Number of Figures: 0
Number of Tables: 2

ISSN: 0014-3022 (Print)
eISSN: 1421-9913 (Online)

For additional information: http://www.karger.com/ENE


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Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in goverment regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
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