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Vol. 49, No. 5, 2005
Issue release date: September–October 2005
Section title: Original Paper
Ann Nutr Metab 2005;49:319–324
(DOI:10.1159/000087336)

Honey-Induced Stimulation of Blood Ethanol Elimination and Its Influence on Serum Triacylglycerol and Blood Pressure in Man

Onyesom I.
Department of Medical Biochemistry, Delta State University, Abraka, Nigeria

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Article / Publication Details

First-Page Preview
Abstract of Original Paper

Received: 10/27/2004
Accepted: 3/23/2005
Published online: 9/15/2005

Number of Print Pages: 6
Number of Figures: 0
Number of Tables: 3

ISSN: 0250-6807 (Print)
eISSN: 1421-9697 (Online)

For additional information: http://www.karger.com/ANM

Abstract

The effect of honey on blood alcohol metabolism and the accompanying changes in serum triacylglycerol and blood pressure were investigated using volunteers. Fifty consenting undergraduates in apparent good health, between the ages of 15 and 30 years (23.6 ± 7.4), were recruited for the study. The subjects were moderate alcohol drinkers (<30 g ethanol/day), matched in body weight and frame size. The participants were given ethanol (0.5 g/kg) and ethanol + honey (0.5 g/kg + 1.25 ml/kg) on two different occasions separated by 1 week. The results show that honey significantly (p < 0.01) increased blood alcohol disappearance and elimination rates by 32.4 and 28.6%, respectively, but reduced the intoxication time (that is, the time taken to attain zero blood alcohol level) and its degree (the peak blood alcohol level) by 30.0 and 4.4%. Ethanol + honey further increased serum triacylglycerol and blood pressure by 20.8 and 1.3/1.4% when compared with the proportion induced by ethanol after about 10 h of ingestion. The occasional use of honey as an anti-intoxicanting agent may be approved. Meanwhile, further studies on how to ameliorate or prevent the associated increase in serum triacylglycerol and blood pressure is required.


  

Author Contacts

I. Onyesom
Department of Medical Biochemistry, Delta State University
PO Box 144
Abraka (Nigeria)
Tel. +234 8030528016, E-Mail onyesominno@yahoo.co.uk

  

Article Information

Received: October 27, 2004
Accepted: March 23, 2005
Published online: August 4, 2005
Number of Print Pages : 6
Number of Figures : 0, Number of Tables : 3, Number of References : 45

  

Publication Details

Annals of Nutrition and Metabolism (European Journal of Nutrition, Metabolic Diseases and Dietetics)

Vol. 49, No. 5, Year 2005 (Cover Date: September-October 2005)

Journal Editor: Elmadfa, I. (Vienna)
ISSN: 0250–6807 (print), 1421–9697 (Online)

For additional information: http://www.karger.com/anm


Article / Publication Details

First-Page Preview
Abstract of Original Paper

Received: 10/27/2004
Accepted: 3/23/2005
Published online: 9/15/2005

Number of Print Pages: 6
Number of Figures: 0
Number of Tables: 3

ISSN: 0250-6807 (Print)
eISSN: 1421-9697 (Online)

For additional information: http://www.karger.com/ANM


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Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in goverment regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
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