Background: Most criticism of homeopathy concerns the
lack of scientific bases and theoretical models. Fundamental
research could make important contributions to our understanding
of the mechanisms of action of homeopathic treatments.
Plant-based bioassays are suitable for basic research
- lacking the placebo effect and ensuring large data samples
for structured statistical analyses. Objective: The aim
of this study was to reproduce a previous experiment on the
effects of arsenic trioxide (As2O3) high dilutions on wheat
seedling growth in order to verify whether the same significant
results could be obtained working in a different place
and with a different experimental team. A further goal was
to investigate high dilution effects on variability. Material
and Methods: A structured experiment was performed blind
over 9 weeks, using wheat seeds previously stressed with a
sublethal dose of As2O3. The seeds were then treated with
either potentized As2O3 (5x, 15x, 25x, 35x, 45x), potentized
water (equivalent potencies) or diluted As2O3 (10-5, 10-15,
10-25, 10-35, 10-45). The working variable was the stem
length, measured after 4, 5, 6 and 7 days. Results: Some potencies
(As2O3 45x and H2O 45x) induced a relevant increase
in seedling growth and/or a variability decrease. Diluted
As2O3 did not induce any significant results. Conclusions:
Confirmation of a significant stimulating effect on seedling
growth and a significant decrease of variability was obtained
with ultra-high dilutions at the 45x potency. The
model of wheat germination and growth has been confirmed
to be a good tool for basic research in homeopathy.
Copyright / Drug Dosage
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