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Case Report

Sweet’s Syndrome – An Extraintestinal Manifestation in Inflammatory Bowel Disease

Ytting H.a · Vind I.a · Bang D.b · Munkholm P.c

Author affiliations

Departments of aMedical Gastroenterology and bClinical Microbiology, Hvidovre Hospital, University of Copenhagen, Hvidovre, and cDepartment of Medical Gastroenterology, Herlev Hospital, University of Copenhagen, Herlev, Denmark

Related Articles for ""

Digestion 2005;72:195–200

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Article / Publication Details

First-Page Preview
Abstract of Case Report

Received: February 04, 2005
Accepted: July 08, 2005
Published online: October 10, 2005
Issue release date: October 2005

Number of Print Pages: 6
Number of Figures: 4
Number of Tables: 0

ISSN: 0012-2823 (Print)
eISSN: 1421-9867 (Online)

For additional information: http://www.karger.com/DIG

Abstract

Background/Aims: Sweet’s syndrome (SS) is a severe dermatosis that may be an extraintestinal manifestation of inflammatory bowel disease (IBD). Worldwide, 35 cases of SS associated with IBD have been reported. We present the first case of severe, recurrent SS in combination with amebic infection and ulcerative colitis complicated with multiple other extraintestinal manifestations. Methods: Disease course was monitored by serum YKL-40 and C-reactive protein (CRP), white blood cell count, albumin and the Simple Clinical Colitis Activity Index (SSCAI). The amebic infection was diagnosed by direct microscopy of wet mount scrapings sampled by repetitive sigmoidoscopies. Results: The patient was diagnosed with left-sided ulcerative colitis and SS combined with extraintestinal manifestations: arthropathies, iridocyclitis and erythema nodosum. Cysts of Entamoeba histolytica were detected in the stools in two separate periods of time. Serum YKL-40 increased prior to CRP and correlated with disease activity, SCCAI, CRP, white blood cell count and inversely with serum albumin. Conclusion: This case gives further support for SS being an extraintestinal manifestation of ulcerative colitis. YKL-40 may be useful in monitoring the disease course of IBD.

© 2005 S. Karger AG, Basel


Article / Publication Details

First-Page Preview
Abstract of Case Report

Received: February 04, 2005
Accepted: July 08, 2005
Published online: October 10, 2005
Issue release date: October 2005

Number of Print Pages: 6
Number of Figures: 4
Number of Tables: 0

ISSN: 0012-2823 (Print)
eISSN: 1421-9867 (Online)

For additional information: http://www.karger.com/DIG


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