The Effect of Adding Calcium Lactate to Xylitol Chewing Gum on Remineralization of Enamel LesionsSuda R. · Suzuki T. · Takiguchi R. · Egawa K. · Sano T. · Hasegawa K.
aDepartment of Periodontology and bFirst Department of Oral Anatomy, Showa University Dental School, Tokyo, Japan
The purpose of the study was to determine whether adding calcium lactate to chewing gum containing xylitol enhances remineralization of enamel surfaces using an early caries lesion model. Enamel slabs were cut from human extracted sound teeth and artificial subsurface lesions created within each. Half the enamel slabs were used as controls and stored in a humidifier while half were mounted into oral appliances worn by 10 volunteers (22–27 years old, 2 males and 8 females) in a three-leg trial, during which they wore the appliance without chewing gum, chewed gum containing xylitol + calcium lactate or chewed gum containing only xylitol 4 times a day for 2 weeks. Calcium concentrations in the enamel surfaces of control and test slabs were measured by X-ray spectrometry and degrees of remineralization were calculated. The mean degree of remineralization was greater after chewing xylitol-Ca gum (0.46 ± 0.10) than after no gum (0.16 ± 0.14) or after chewing xylitol gum (0.33 ± 0.10) (p < 0.01). In conclusion, chewing gum containing xylitol + calcium lactate could enhance remineralization of enamel surface compared to chewing gum containing only xylitol or no gum chewing.
Department of Periodontology, Showa University Dental School
2-1-1 Kitasenzoku, Ohta-ku, Tokyo 145-1958 (Japan)
Tel. +81 3 3787 1151, ext. 352, Fax +81 3 3787 9290
Received: March 28, 2002
Accepted after revision: February 16, 2005
Number of Print Pages : 4
Number of Figures : 0, Number of Tables : 1, Number of References : 8
Vol. 40, No. 1, Year 2006 (Cover Date: December 2005)
Journal Editor: Shellis, R.P.(Bristol)
ISSN: 0008–6568 (print), 1421–976X (Online)
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