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Vol. 212, Suppl. 1, 2006
Issue release date: February 2006
Section title: Wound Care
Dermatology 2006;212:66–76
(DOI:10.1159/000089202)

What Is the Evidence for Tissue Regeneration Impairment when Using a Formulation of PVP-I Antiseptic on Open Wounds?

Banwell H.
School of Health Sciences, University of South Australia, Adelaide, Australia

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Article / Publication Details

First-Page Preview
Abstract of Wound Care

Published online: 2/22/2006
Issue release date: February 2006

Number of Print Pages: 11
Number of Figures: 0
Number of Tables: 13

ISSN: 1018-8665 (Print)
eISSN: 1421-9832 (Online)

For additional information: http://www.karger.com/DRM

Abstract

Wound care and the use of antiseptics has long been the subject of much debate within the health professional’s literature. This study was undertaken to determine the range of literature available on povidone-iodine (PVP-I) antiseptic use and the evidence supporting the outcomes reported. A range of articles was collected and divided into subgroups based on hierarchy of evidence and the five evidence dimensions [1]. Using the READER® scoring tool, articles were evaluated and given a numerical award between 4 and 25 as a determinant of their quality in method, statistical analysis and outcome measures, with those scoring 12.5 or higher (from a possible 25) deemed as offering a satisfactory level of evidence. Statistical analysis on the results prior to applying the READER scoring tool found that overall 49% of articles did not support PVP-I use. However, this situation changed when the quality of evidence was limited to articles scoring >12.5. The higher-scored articles showed a 71% support for the continued use of PVP-I. The outcome of this study shows that there is reason for further debate over the use of PVP-I.


  

Author Contacts

Helen Banwell
School of Health Sciences, University of South Australia
GPO Box 2471
Adelaide, SA 5001 (Australia)
Tel. +61 8 8302 2589, Fax +61 8 8302 2766, E-Mail helen.banwell@unisa.edu.au

  

Article Information

Number of Print Pages : 11
Number of Figures : 0, Number of Tables : 13, Number of References : 49

  

Publication Details

Dermatology

Vol. 212, No. Suppl. 1, Year 2006 (Cover Date: February 2006)

Journal Editor: Saurat, J.-H. (Geneva)
ISSN: 1018–8665 (print), 1421–9832 (Online)

For additional information: http://www.karger.com/DRM


Article / Publication Details

First-Page Preview
Abstract of Wound Care

Published online: 2/22/2006
Issue release date: February 2006

Number of Print Pages: 11
Number of Figures: 0
Number of Tables: 13

ISSN: 1018-8665 (Print)
eISSN: 1421-9832 (Online)

For additional information: http://www.karger.com/DRM


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Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in goverment regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
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